Identification of secretory IgA, free secretory piece and serum IgA in the ovine and caprine species
Caprine and ovine IgA were identified by cross-reaction with anti-human and anti-bovine IgA sera in colostrum, mature milk, saliva, urine and serum. Secretory component (SC) was shown in the free form and associated with polymeric serum IgA in secretions. Mean molecular weights were determined for t...
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| Veröffentlicht in: | Immunochemistry (1965) 1970-08, Vol.7 (8), p.679-682 |
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| container_title | Immunochemistry (1965) |
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| creator | Pahud, J.J. Mach, J.P. |
| description | Caprine and ovine IgA were identified by cross-reaction with anti-human and anti-bovine IgA sera in colostrum, mature milk, saliva, urine and serum. Secretory component (SC) was shown in the free form and associated with polymeric serum IgA in secretions. Mean molecular weights were determined for the IgA and the free secretory components. The high IgA content of saliva suggested that it was a major secretory immunoglobulin in these species. Traces of secretory IgA were also found in normal sera but most of the serum IgA had no secretory determinant. Secretory IgA, serum IgA and free secretory component were purified. Levels of the sheep and goat immunoglobulins were measured in various fluids. |
| doi_str_mv | 10.1016/0019-2791(70)90174-6 |
| format | Article |
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Secretory component (SC) was shown in the free form and associated with polymeric serum IgA in secretions. Mean molecular weights were determined for the IgA and the free secretory components. The high IgA content of saliva suggested that it was a major secretory immunoglobulin in these species. Traces of secretory IgA were also found in normal sera but most of the serum IgA had no secretory determinant. Secretory IgA, serum IgA and free secretory component were purified. 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Secretory component (SC) was shown in the free form and associated with polymeric serum IgA in secretions. Mean molecular weights were determined for the IgA and the free secretory components. The high IgA content of saliva suggested that it was a major secretory immunoglobulin in these species. Traces of secretory IgA were also found in normal sera but most of the serum IgA had no secretory determinant. Secretory IgA, serum IgA and free secretory component were purified. Levels of the sheep and goat immunoglobulins were measured in various fluids.</description><subject>Animals</subject><subject>Cattle</subject><subject>Colostrum - immunology</subject><subject>Epitopes</subject><subject>gamma-Globulins - analysis</subject><subject>gamma-Globulins - urine</subject><subject>Goats</subject><subject>Humans</subject><subject>Immunodiffusion</subject><subject>Immunoglobulins - analysis</subject><subject>Immunoglobulins - urine</subject><subject>Milk - immunology</subject><subject>Molecular Weight</subject><subject>Saliva - immunology</subject><subject>Sheep</subject><issn>0019-2791</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1970</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRb0AlVL4A5CyQiARsBMnzmyQqopHpUpsYG059hiMmgd2Wql_T0KqihUr2_femfEcQi4YvWOU5feUMogTAexa0BugTPA4PyLTg3xCTkP4Gp7AYUImnEJRAEyJWRqsO2edVp1r6qixUUDtsWv8Llp-zG8j6xH_aK1DjZGqTa_5TTVkIldH3SdGzdbVo6VV64d7aFE7DGfk2Kp1wPP9OSPvT49vi5d49fq8XMxXsU4z0cWF4ZxDwhFAJIqLhFpbJCigLJlIWFIUSZkyMKJkiCbPQGWZyalFbjOqQKUzcjX2bX3zvcHQycoFjeu1qrHZBFlQkRY5QB_kY1D7JgSPVvb_rZTfSUblAFQOqORATgoqf4HKvC-73PfflBWaQ9GeZu8_jD72S24dehn69WuNxnnUnTSN-3_AD6BwhoA</recordid><startdate>197008</startdate><enddate>197008</enddate><creator>Pahud, J.J.</creator><creator>Mach, J.P.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197008</creationdate><title>Identification of secretory IgA, free secretory piece and serum IgA in the ovine and caprine species</title><author>Pahud, J.J. ; Mach, J.P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-8d444924e9972a4720ff82e79bb17212882b319d7b1eed659a55d60fe4f50a9a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1970</creationdate><topic>Animals</topic><topic>Cattle</topic><topic>Colostrum - immunology</topic><topic>Epitopes</topic><topic>gamma-Globulins - analysis</topic><topic>gamma-Globulins - urine</topic><topic>Goats</topic><topic>Humans</topic><topic>Immunodiffusion</topic><topic>Immunoglobulins - analysis</topic><topic>Immunoglobulins - urine</topic><topic>Milk - immunology</topic><topic>Molecular Weight</topic><topic>Saliva - immunology</topic><topic>Sheep</topic><toplevel>online_resources</toplevel><creatorcontrib>Pahud, J.J.</creatorcontrib><creatorcontrib>Mach, J.P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Immunochemistry (1965)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pahud, J.J.</au><au>Mach, J.P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of secretory IgA, free secretory piece and serum IgA in the ovine and caprine species</atitle><jtitle>Immunochemistry (1965)</jtitle><addtitle>Immunochemistry</addtitle><date>1970-08</date><risdate>1970</risdate><volume>7</volume><issue>8</issue><spage>679</spage><epage>682</epage><pages>679-682</pages><issn>0019-2791</issn><abstract>Caprine and ovine IgA were identified by cross-reaction with anti-human and anti-bovine IgA sera in colostrum, mature milk, saliva, urine and serum. Secretory component (SC) was shown in the free form and associated with polymeric serum IgA in secretions. Mean molecular weights were determined for the IgA and the free secretory components. The high IgA content of saliva suggested that it was a major secretory immunoglobulin in these species. Traces of secretory IgA were also found in normal sera but most of the serum IgA had no secretory determinant. Secretory IgA, serum IgA and free secretory component were purified. Levels of the sheep and goat immunoglobulins were measured in various fluids.</abstract><cop>England</cop><pub>Elsevier B.V</pub><pmid>4098899</pmid><doi>10.1016/0019-2791(70)90174-6</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0019-2791 |
| ispartof | Immunochemistry (1965), 1970-08, Vol.7 (8), p.679-682 |
| issn | 0019-2791 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80738699 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Cattle Colostrum - immunology Epitopes gamma-Globulins - analysis gamma-Globulins - urine Goats Humans Immunodiffusion Immunoglobulins - analysis Immunoglobulins - urine Milk - immunology Molecular Weight Saliva - immunology Sheep |
| title | Identification of secretory IgA, free secretory piece and serum IgA in the ovine and caprine species |
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