Different interactions of platelets with arterial and venous coronary bypass vessels

We studied the interaction of platelets with the wall of human internal mammary arteries and saphenous veins, suspended in organ chambers for measurement of isometric tension. Vessels were obtained during coronary bypass surgery and cut into 5 mm rings; in some the endothelium was chemically removed...

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Veröffentlicht in:	The Lancet (British edition) 1991-04, Vol.337 (8747), p.939-943
Hauptverfasser:	Yang, Z., Luscher, T.F., Lüscher, T.F., Stulz, P., von Segesser, L., Bauer, E., Turina, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apyrase - pharmacology Arginine - analogs & derivatives Arginine - pharmacology Aspirin - pharmacology Biological and medical sciences Blood coagulation. Blood cells Blood Platelets - metabolism Circulatory system Coronary Artery Bypass Dose-Response Relationship, Drug Drugs Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Fundamental and applied biological sciences. Psychology Humans In Vitro Techniques Indomethacin - pharmacology Isometric Contraction - drug effects Ketanserin - pharmacology Mammary Arteries - metabolism Medical research Molecular and cellular biology Muscle, Smooth, Vascular - drug effects Nitric oxide Norepinephrine - pharmacology omega-N-Methylarginine Platelet Aggregation - drug effects Saphenous Vein - metabolism Thromboxane A2 - analogs & derivatives Thromboxane A2 - antagonists & inhibitors Thromboxane A2 - pharmacology
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