Histopathology of Incipient Fundus Flavimaculatus
A 9-year-old boy was diagnosed with fundus flavimaculatus in his left eye. The boy's fellow eye was enucleated at 16 months of age for retinoblastoma. The authors reviewed the material submitted for histopathologic examination and found that the retinal pigment epithelial cells demonstrated inc...
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| Veröffentlicht in: | Ophthalmology (Rochester, Minn.) Minn.), 1991-06, Vol.98 (6), p.953-956 |
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| container_issue | 6 |
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| container_title | Ophthalmology (Rochester, Minn.) |
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| creator | Steinmetz, Robert L. Garner, Alec Maguire, Joseph I. Bird, Alan C. |
| description | A 9-year-old boy was diagnosed with fundus flavimaculatus in his left eye. The boy's fellow eye was enucleated at 16 months of age for retinoblastoma. The authors reviewed the material submitted for histopathologic examination and found that the retinal pigment epithelial cells demonstrated increased autofluorescence and increased reactivity to periodic acid-Schiff staining. Many cells had their melanin granules displaced toward the cell apex. The retinal pigment epithelial changes are consistent with previous histopathologic findings in fundus flavimaculatus and imply that the structural changes are seen in early life. |
| doi_str_mv | 10.1016/S0161-6420(91)32197-3 |
| format | Article |
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The boy's fellow eye was enucleated at 16 months of age for retinoblastoma. The authors reviewed the material submitted for histopathologic examination and found that the retinal pigment epithelial cells demonstrated increased autofluorescence and increased reactivity to periodic acid-Schiff staining. Many cells had their melanin granules displaced toward the cell apex. The retinal pigment epithelial changes are consistent with previous histopathologic findings in fundus flavimaculatus and imply that the structural changes are seen in early life.</description><identifier>ISSN: 0161-6420</identifier><identifier>EISSN: 1549-4713</identifier><identifier>DOI: 10.1016/S0161-6420(91)32197-3</identifier><identifier>PMID: 1866150</identifier><identifier>CODEN: OPHTDG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Biological and medical sciences ; Child ; Eye Enucleation ; Fluorescein Angiography ; Fundus Oculi ; Humans ; Lipofuscin - metabolism ; Male ; Medical sciences ; Ophthalmology ; Pigment Epithelium of Eye - pathology ; Retinal Diseases - pathology ; Retinoblastoma - pathology ; Retinopathies</subject><ispartof>Ophthalmology (Rochester, Minn.), 1991-06, Vol.98 (6), p.953-956</ispartof><rights>1991 American Academy of Ophthalmology, Inc</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c390t-241e685f26740cdb98346efcffb45475b0634d4cf63717ef9776d6d5cb703abe3</citedby><cites>FETCH-LOGICAL-c390t-241e685f26740cdb98346efcffb45475b0634d4cf63717ef9776d6d5cb703abe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0161642091321973$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19707780$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1866150$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Steinmetz, Robert L.</creatorcontrib><creatorcontrib>Garner, Alec</creatorcontrib><creatorcontrib>Maguire, Joseph I.</creatorcontrib><creatorcontrib>Bird, Alan C.</creatorcontrib><title>Histopathology of Incipient Fundus Flavimaculatus</title><title>Ophthalmology (Rochester, Minn.)</title><addtitle>Ophthalmology</addtitle><description>A 9-year-old boy was diagnosed with fundus flavimaculatus in his left eye. The boy's fellow eye was enucleated at 16 months of age for retinoblastoma. The authors reviewed the material submitted for histopathologic examination and found that the retinal pigment epithelial cells demonstrated increased autofluorescence and increased reactivity to periodic acid-Schiff staining. Many cells had their melanin granules displaced toward the cell apex. The retinal pigment epithelial changes are consistent with previous histopathologic findings in fundus flavimaculatus and imply that the structural changes are seen in early life.</description><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Eye Enucleation</subject><subject>Fluorescein Angiography</subject><subject>Fundus Oculi</subject><subject>Humans</subject><subject>Lipofuscin - metabolism</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Ophthalmology</subject><subject>Pigment Epithelium of Eye - pathology</subject><subject>Retinal Diseases - pathology</subject><subject>Retinoblastoma - pathology</subject><subject>Retinopathies</subject><issn>0161-6420</issn><issn>1549-4713</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkD1PwzAQhi0EKqXwEyplAcEQsGPHjieEKkorVWIAZsvxBxilcYiTSv33uE1FR5a74Z67e_UAMEXwHkFEH95iQSklGbzl6A5niLMUn4AxyglPCUP4FIz_kHNwEcI3hJBSTEZghApKUQ7HAC1c6Hwjuy9f-c9t4m2yrJVrnKm7ZN7Xug_JvJIbt5aqr2TXh0twZmUVzNWhT8DH_Pl9tkhXry_L2dMqVZjDLs0IMrTIbUYZgUqXvMCEGqusLUlOWF7CmEQTZSlmiBnLGaOa6lyVDGJZGjwBN8PdpvU_vQmdWLugTFXJ2vg-iAKyjFNSRDAfQNX6EFpjRdPGuO1WICh2qsReldh5EByJvSqB49708KAv10YftwY3cX59mMugZGVbGcWEI8YZZKzYcY8DZ6KNjTOtCCrqU0a71qhOaO_-SfILCm6EsQ</recordid><startdate>19910601</startdate><enddate>19910601</enddate><creator>Steinmetz, Robert L.</creator><creator>Garner, Alec</creator><creator>Maguire, Joseph I.</creator><creator>Bird, Alan C.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19910601</creationdate><title>Histopathology of Incipient Fundus Flavimaculatus</title><author>Steinmetz, Robert L. ; Garner, Alec ; Maguire, Joseph I. ; Bird, Alan C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c390t-241e685f26740cdb98346efcffb45475b0634d4cf63717ef9776d6d5cb703abe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Eye Enucleation</topic><topic>Fluorescein Angiography</topic><topic>Fundus Oculi</topic><topic>Humans</topic><topic>Lipofuscin - metabolism</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Ophthalmology</topic><topic>Pigment Epithelium of Eye - pathology</topic><topic>Retinal Diseases - pathology</topic><topic>Retinoblastoma - pathology</topic><topic>Retinopathies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Steinmetz, Robert L.</creatorcontrib><creatorcontrib>Garner, Alec</creatorcontrib><creatorcontrib>Maguire, Joseph I.</creatorcontrib><creatorcontrib>Bird, Alan C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Ophthalmology (Rochester, Minn.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Steinmetz, Robert L.</au><au>Garner, Alec</au><au>Maguire, Joseph I.</au><au>Bird, Alan C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Histopathology of Incipient Fundus Flavimaculatus</atitle><jtitle>Ophthalmology (Rochester, Minn.)</jtitle><addtitle>Ophthalmology</addtitle><date>1991-06-01</date><risdate>1991</risdate><volume>98</volume><issue>6</issue><spage>953</spage><epage>956</epage><pages>953-956</pages><issn>0161-6420</issn><eissn>1549-4713</eissn><coden>OPHTDG</coden><abstract>A 9-year-old boy was diagnosed with fundus flavimaculatus in his left eye. 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| ispartof | Ophthalmology (Rochester, Minn.), 1991-06, Vol.98 (6), p.953-956 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Biological and medical sciences Child Eye Enucleation Fluorescein Angiography Fundus Oculi Humans Lipofuscin - metabolism Male Medical sciences Ophthalmology Pigment Epithelium of Eye - pathology Retinal Diseases - pathology Retinoblastoma - pathology Retinopathies |
| title | Histopathology of Incipient Fundus Flavimaculatus |
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