A randomized controlled trial of intermittent compared with daily cotrimoxazole preventive therapy in HIV-infected children

Cotrimoxazole preventive therapy (CPT) reduces morbidity and mortality in HIV-infected children. The WHO recommends prolonged daily CPT for HIV-infected infants and children. In adults, intermittent CPT has been associated with less adverse events than daily, with increased tolerability and equal ef...

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Veröffentlicht in:	AIDS (London) 2010-09, Vol.24 (14), p.2225-2232
Hauptverfasser:	ZAR, Heather J, WORKMAN, Lesley, COTTON, Mark F, LE ROUX, Stanzi M, JENNINGS, Teresa, JELE, Nomawethu, SCHAAF, Hendrick Simon, BARCLAY-LOGGIE, Ann, MULLIGAN, Chris, LE ROUX, David M, LOMBARD, Carl J
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Anti-Infective Agents - administration & dosage Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral Therapy, Highly Active - methods Biological and medical sciences Child, Preschool Female HIV Infections - drug therapy HIV Infections - immunology HIV Infections - mortality HIV-1 Hospitalization - statistics & numerical data Human immunodeficiency virus Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infant Infectious diseases Male Medical sciences Pharmacology. Drug treatments Prospective Studies Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Zambia - epidemiology
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