Malignant hyperthermia and related neuromuscular diseases: Caffeine contracture of the skinned muscle fibers
Using the skinned fiber preparation, the response to caffeine was studied on the skeletal muscle of malignant hyperthermia or other neuromuscular diseases. The sensitivity to caffeine was increased in the muscle of malignant hyperthermia. The sensitivity also was increased in Duchenne muscular dystr...
Gespeichert in:
| Veröffentlicht in: | Muscle & nerve 1983-09, Vol.6 (7), p.510-514 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 514 |
|---|---|
| container_issue | 7 |
| container_start_page | 510 |
| container_title | Muscle & nerve |
| container_volume | 6 |
| creator | Takagi, Akio Sunohara, Nobuhiko Ishihara, Tadayuki Nonaka, Ikuya Sugita, Hideo |
| description | Using the skinned fiber preparation, the response to caffeine was studied on the skeletal muscle of malignant hyperthermia or other neuromuscular diseases. The sensitivity to caffeine was increased in the muscle of malignant hyperthermia. The sensitivity also was increased in Duchenne muscular dystrophy or asymptomatic patients with raised serum creatine kinase activity. Judging from the interaction between caffeine and the contractile system, the abnormal response originated from the sarcoplasmic reticulum in malignant hyperthermia. In Duchenne muscular dystrophy, the contractile system also might be involved in the increased sensitivity. Since the disease spectrum presenting abnormal responses is broad, it is suggested that muscle fibers become sensitive to caffeine when they are degenerating or regenerating. |
| doi_str_mv | 10.1002/mus.880060707 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_80728378</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>80728378</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4697-ee25bd5cf0a946124621058743fa3f346269c0a371b7eb8e60fe2cad3a654b2b3</originalsourceid><addsrcrecordid>eNp9kEtv1DAUhS0EKkNhyRLJC8QuxYkd22GHRtAipiAEVRGb6Ma5pqaOM7UTwfz7ejRhxIqVZd3vPHQIeV6ys5Kx6vUwpzOtGZNMMfWArErWqELUjX5IVqwUupC8-f6YPEnpF2Os1FKdkBMpOa-lWBF_Cd79DBAmerPbYpxuMA4OKISeRvQwYU8DznHMMWb2EGnvEkLC9IauwVp0AakZwxTBTHNEOlqaPWi6dSFk7V7mkVrXYUxPySMLPuGz5T0lV-_ffVtfFJvP5x_WbzeFETKXR6zqrq-NZdAIWVZCViWrtRLcArc8f2VjGHBVdgo7jZJZrAz0HGQtuqrjp-TVwXcbx7sZ09QOLhn0HgKOc2o1U5XmSmewOIAmjilFtO02ugHiri1Zu1-3Hfb433Uz_2IxnrsB-yO9zJnvL5c7JAPeRgjGpSPWZErwvY06YL-dx93_M9vLq6__FlgKuzThn6MS4m0rFVd1e_3pvL3-uPnC1uJHzrsHqESj1g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>80728378</pqid></control><display><type>article</type><title>Malignant hyperthermia and related neuromuscular diseases: Caffeine contracture of the skinned muscle fibers</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Takagi, Akio ; Sunohara, Nobuhiko ; Ishihara, Tadayuki ; Nonaka, Ikuya ; Sugita, Hideo</creator><creatorcontrib>Takagi, Akio ; Sunohara, Nobuhiko ; Ishihara, Tadayuki ; Nonaka, Ikuya ; Sugita, Hideo</creatorcontrib><description>Using the skinned fiber preparation, the response to caffeine was studied on the skeletal muscle of malignant hyperthermia or other neuromuscular diseases. The sensitivity to caffeine was increased in the muscle of malignant hyperthermia. The sensitivity also was increased in Duchenne muscular dystrophy or asymptomatic patients with raised serum creatine kinase activity. Judging from the interaction between caffeine and the contractile system, the abnormal response originated from the sarcoplasmic reticulum in malignant hyperthermia. In Duchenne muscular dystrophy, the contractile system also might be involved in the increased sensitivity. Since the disease spectrum presenting abnormal responses is broad, it is suggested that muscle fibers become sensitive to caffeine when they are degenerating or regenerating.</description><identifier>ISSN: 0148-639X</identifier><identifier>EISSN: 1097-4598</identifier><identifier>DOI: 10.1002/mus.880060707</identifier><identifier>PMID: 6633564</identifier><identifier>CODEN: MUNEDE</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Adult ; Aged ; Anesthesia ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Caffeine - pharmacology ; Child ; General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation ; Humans ; In Vitro Techniques ; Malignant Hyperthermia - physiopathology ; Medical sciences ; Middle Aged ; Muscle Contraction - drug effects ; Muscles - physiopathology ; Muscular Dystrophies - physiopathology ; Neuromuscular Diseases - physiopathology ; Stimulation, Chemical</subject><ispartof>Muscle & nerve, 1983-09, Vol.6 (7), p.510-514</ispartof><rights>Copyright © 1983 John Wiley & Sons, Inc.</rights><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4697-ee25bd5cf0a946124621058743fa3f346269c0a371b7eb8e60fe2cad3a654b2b3</citedby><cites>FETCH-LOGICAL-c4697-ee25bd5cf0a946124621058743fa3f346269c0a371b7eb8e60fe2cad3a654b2b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmus.880060707$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmus.880060707$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9335437$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6633564$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Takagi, Akio</creatorcontrib><creatorcontrib>Sunohara, Nobuhiko</creatorcontrib><creatorcontrib>Ishihara, Tadayuki</creatorcontrib><creatorcontrib>Nonaka, Ikuya</creatorcontrib><creatorcontrib>Sugita, Hideo</creatorcontrib><title>Malignant hyperthermia and related neuromuscular diseases: Caffeine contracture of the skinned muscle fibers</title><title>Muscle & nerve</title><addtitle>Muscle Nerve</addtitle><description>Using the skinned fiber preparation, the response to caffeine was studied on the skeletal muscle of malignant hyperthermia or other neuromuscular diseases. The sensitivity to caffeine was increased in the muscle of malignant hyperthermia. The sensitivity also was increased in Duchenne muscular dystrophy or asymptomatic patients with raised serum creatine kinase activity. Judging from the interaction between caffeine and the contractile system, the abnormal response originated from the sarcoplasmic reticulum in malignant hyperthermia. In Duchenne muscular dystrophy, the contractile system also might be involved in the increased sensitivity. Since the disease spectrum presenting abnormal responses is broad, it is suggested that muscle fibers become sensitive to caffeine when they are degenerating or regenerating.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Anesthesia</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Caffeine - pharmacology</subject><subject>Child</subject><subject>General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>Malignant Hyperthermia - physiopathology</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Muscle Contraction - drug effects</subject><subject>Muscles - physiopathology</subject><subject>Muscular Dystrophies - physiopathology</subject><subject>Neuromuscular Diseases - physiopathology</subject><subject>Stimulation, Chemical</subject><issn>0148-639X</issn><issn>1097-4598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtv1DAUhS0EKkNhyRLJC8QuxYkd22GHRtAipiAEVRGb6Ma5pqaOM7UTwfz7ejRhxIqVZd3vPHQIeV6ys5Kx6vUwpzOtGZNMMfWArErWqELUjX5IVqwUupC8-f6YPEnpF2Os1FKdkBMpOa-lWBF_Cd79DBAmerPbYpxuMA4OKISeRvQwYU8DznHMMWb2EGnvEkLC9IauwVp0AakZwxTBTHNEOlqaPWi6dSFk7V7mkVrXYUxPySMLPuGz5T0lV-_ffVtfFJvP5x_WbzeFETKXR6zqrq-NZdAIWVZCViWrtRLcArc8f2VjGHBVdgo7jZJZrAz0HGQtuqrjp-TVwXcbx7sZ09QOLhn0HgKOc2o1U5XmSmewOIAmjilFtO02ugHiri1Zu1-3Hfb433Uz_2IxnrsB-yO9zJnvL5c7JAPeRgjGpSPWZErwvY06YL-dx93_M9vLq6__FlgKuzThn6MS4m0rFVd1e_3pvL3-uPnC1uJHzrsHqESj1g</recordid><startdate>198309</startdate><enddate>198309</enddate><creator>Takagi, Akio</creator><creator>Sunohara, Nobuhiko</creator><creator>Ishihara, Tadayuki</creator><creator>Nonaka, Ikuya</creator><creator>Sugita, Hideo</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198309</creationdate><title>Malignant hyperthermia and related neuromuscular diseases: Caffeine contracture of the skinned muscle fibers</title><author>Takagi, Akio ; Sunohara, Nobuhiko ; Ishihara, Tadayuki ; Nonaka, Ikuya ; Sugita, Hideo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4697-ee25bd5cf0a946124621058743fa3f346269c0a371b7eb8e60fe2cad3a654b2b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Anesthesia</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Caffeine - pharmacology</topic><topic>Child</topic><topic>General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>Malignant Hyperthermia - physiopathology</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Muscle Contraction - drug effects</topic><topic>Muscles - physiopathology</topic><topic>Muscular Dystrophies - physiopathology</topic><topic>Neuromuscular Diseases - physiopathology</topic><topic>Stimulation, Chemical</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Takagi, Akio</creatorcontrib><creatorcontrib>Sunohara, Nobuhiko</creatorcontrib><creatorcontrib>Ishihara, Tadayuki</creatorcontrib><creatorcontrib>Nonaka, Ikuya</creatorcontrib><creatorcontrib>Sugita, Hideo</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Muscle & nerve</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Takagi, Akio</au><au>Sunohara, Nobuhiko</au><au>Ishihara, Tadayuki</au><au>Nonaka, Ikuya</au><au>Sugita, Hideo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Malignant hyperthermia and related neuromuscular diseases: Caffeine contracture of the skinned muscle fibers</atitle><jtitle>Muscle & nerve</jtitle><addtitle>Muscle Nerve</addtitle><date>1983-09</date><risdate>1983</risdate><volume>6</volume><issue>7</issue><spage>510</spage><epage>514</epage><pages>510-514</pages><issn>0148-639X</issn><eissn>1097-4598</eissn><coden>MUNEDE</coden><abstract>Using the skinned fiber preparation, the response to caffeine was studied on the skeletal muscle of malignant hyperthermia or other neuromuscular diseases. The sensitivity to caffeine was increased in the muscle of malignant hyperthermia. The sensitivity also was increased in Duchenne muscular dystrophy or asymptomatic patients with raised serum creatine kinase activity. Judging from the interaction between caffeine and the contractile system, the abnormal response originated from the sarcoplasmic reticulum in malignant hyperthermia. In Duchenne muscular dystrophy, the contractile system also might be involved in the increased sensitivity. Since the disease spectrum presenting abnormal responses is broad, it is suggested that muscle fibers become sensitive to caffeine when they are degenerating or regenerating.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>6633564</pmid><doi>10.1002/mus.880060707</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0148-639X |
| ispartof | Muscle & nerve, 1983-09, Vol.6 (7), p.510-514 |
| issn | 0148-639X 1097-4598 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80728378 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Adolescent Adult Aged Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Caffeine - pharmacology Child General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation Humans In Vitro Techniques Malignant Hyperthermia - physiopathology Medical sciences Middle Aged Muscle Contraction - drug effects Muscles - physiopathology Muscular Dystrophies - physiopathology Neuromuscular Diseases - physiopathology Stimulation, Chemical |
| title | Malignant hyperthermia and related neuromuscular diseases: Caffeine contracture of the skinned muscle fibers |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T09%3A12%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Malignant%20hyperthermia%20and%20related%20neuromuscular%20diseases:%20Caffeine%20contracture%20of%20the%20skinned%20muscle%20fibers&rft.jtitle=Muscle%20&%20nerve&rft.au=Takagi,%20Akio&rft.date=1983-09&rft.volume=6&rft.issue=7&rft.spage=510&rft.epage=514&rft.pages=510-514&rft.issn=0148-639X&rft.eissn=1097-4598&rft.coden=MUNEDE&rft_id=info:doi/10.1002/mus.880060707&rft_dat=%3Cproquest_cross%3E80728378%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=80728378&rft_id=info:pmid/6633564&rfr_iscdi=true |