Long-Term Treatment of Central Precocious Puberty with a Long-Acting Analogue of Luteinizing Hormone-Releasing Hormone: Effects on Somatic Growth and Skeletal Maturation

The gonadotropin-releasing hormone–like agonist d-Trp 6 -Pro 9 -NEt-LHRH (LHRH a ) has been shown to induce a reversible short-term suppression of gonadotropins and gonadal steroids in patients with central precocious puberty. Since accelerated statural growth and bone maturation are clinical featur...

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Veröffentlicht in:	The New England journal of medicine 1983-11, Vol.309 (21), p.1286-1290
Hauptverfasser:	Mansfield, M.Joan, Beardsworth, Donna E, Loughlin, Jacquelyn S, Crawford, John D, Bode, Hans H, Rivier, Jean, Vale, Wylie, Kushner, David C, Crigler, John F, Crowley, William F
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age Determination by Skeleton Biological and medical sciences Body Height - drug effects Bone Development - drug effects Child Child, Preschool Female Follicle Stimulating Hormone - blood Genital system. Reproduction Gonadotropin-Releasing Hormone - adverse effects Gonadotropin-Releasing Hormone - analogs & derivatives Gonadotropin-Releasing Hormone - pharmacology Gonadotropin-Releasing Hormone - therapeutic use Growth - drug effects Growth rate Humans Long-Term Care Luteinizing Hormone - blood Medical sciences Patients Pharmacology. Drug treatments Physical growth Puberty, Precocious - drug therapy Sexual Maturation - drug effects Triptorelin Pamoate - analogs & derivatives
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