Production of stress-inducible form of heat-shock protein 70 in mouse peritoneal adherent cells afterin Vivo infection byFrancisella tularensis
Heat-shock proteins (hsp) are ubiquitously produced molecules which participate in the protection of cells from environmental perturbation. Moreover, the members of the heat-shock protein 60 (hsp60) and 70 (hsp70) families play an important role in pathogen-host interactions. We studiedin vivo produ...
Gespeichert in:
| Veröffentlicht in: | Folia microbiologica 1999-06, Vol.44 (3), p.306-310 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 310 |
|---|---|
| container_issue | 3 |
| container_start_page | 306 |
| container_title | Folia microbiologica |
| container_volume | 44 |
| creator | Stulík, J. Hernychová, L. Macela, A. Kročová, Z. Kroča, M. |
| description | Heat-shock proteins (hsp) are ubiquitously produced molecules which participate in the protection of cells from environmental perturbation. Moreover, the members of the heat-shock protein 60 (hsp60) and 70 (hsp70) families play an important role in pathogen-host interactions. We studiedin vivo production of the 70-kDa heat-shock proteins in the extract of peritoneal exudate cells (PEC) from mice injected intraperitoneally with an attenuated vaccine strain (LVS) ofFrancisella tularensis. We found a differential production of a highly stress-inducible member of the hsp70 family, designated hsp72, in three inbred strains of mice exhibiting either resistance or susceptibility toF. tularensis LVS infection. Whereas in tularemia-resistant mice hsp72 was even expressed in PEC without injection of bacteria and its production further increased on day 3 and slowly declined on days 5 and 7 after injection, in susceptible mice hsp72 production was highly inducble and restricted only to day 3 afterin vivo infection. Further analysis of hsp72 expression revealed intracellular hsp72 accumulation and its preferential production by peritoneal adherent cells. |
| doi_str_mv | 10.1007/BF02818552 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_807273217</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2146534611</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1357-d0af5f444ddab7ae4cc6aed47969ffb4086acb8eb2305307c453a490bc90293d3</originalsourceid><addsrcrecordid>eNpdkU1r3DAQhkVJoJu0l_4CkUuh4HT0ZdnHNmTTwEJ7SHo1sjxilXqljSQH8ivyl6NlC4FcZmDeZz5ehpAvDC4ZgP7-cw28Y51S_ANZsU7LpheqPSErAKYa1Qr-kZzl_ADQghR8RV7-pDgttvgYaHQ0l4Q5Nz7Umh9npC6m3UHYoilN3kb7j-5TLOgD1UBr3MUlI91j8iUGNDM10xYThkItznOmxpWqBfrXP8XKOzzuGp_XyQTrc4UMLctsak_2-RM5dWbO-Pl_Pif36-u7q1_N5vfN7dWPTWOZULqZwDjlpJTTZEZtUFrbGpyk7tveuVFC1xo7djhyAUqAtlIJI3sYbQ-8F5M4J1-Pc6ubxwVzGXY-Hy42AaujoQPNteBMV_LiHfkQlxTqcYNWsmecMV6hb0fIpphzQjfsk9-Z9DwwGA6fGd4-I14BzkWDAA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>754912112</pqid></control><display><type>article</type><title>Production of stress-inducible form of heat-shock protein 70 in mouse peritoneal adherent cells afterin Vivo infection byFrancisella tularensis</title><source>Springer Nature - Complete Springer Journals</source><creator>Stulík, J. ; Hernychová, L. ; Macela, A. ; Kročová, Z. ; Kroča, M.</creator><creatorcontrib>Stulík, J. ; Hernychová, L. ; Macela, A. ; Kročová, Z. ; Kroča, M.</creatorcontrib><description>Heat-shock proteins (hsp) are ubiquitously produced molecules which participate in the protection of cells from environmental perturbation. Moreover, the members of the heat-shock protein 60 (hsp60) and 70 (hsp70) families play an important role in pathogen-host interactions. We studiedin vivo production of the 70-kDa heat-shock proteins in the extract of peritoneal exudate cells (PEC) from mice injected intraperitoneally with an attenuated vaccine strain (LVS) ofFrancisella tularensis. We found a differential production of a highly stress-inducible member of the hsp70 family, designated hsp72, in three inbred strains of mice exhibiting either resistance or susceptibility toF. tularensis LVS infection. Whereas in tularemia-resistant mice hsp72 was even expressed in PEC without injection of bacteria and its production further increased on day 3 and slowly declined on days 5 and 7 after injection, in susceptible mice hsp72 production was highly inducble and restricted only to day 3 afterin vivo infection. Further analysis of hsp72 expression revealed intracellular hsp72 accumulation and its preferential production by peritoneal adherent cells.</description><identifier>ISSN: 0015-5632</identifier><identifier>EISSN: 1874-9356</identifier><identifier>DOI: 10.1007/BF02818552</identifier><language>eng</language><publisher>Dordrecht: Springer Nature B.V</publisher><subject>Adherent cells ; Exudation ; Heat ; Heat shock proteins ; Hsp60 protein ; Hsp70 protein ; Hsp72 protein ; Inbreeding ; Injection ; Medical research ; Peritoneal exudate cells ; Peritoneum ; Perturbation ; Proteins ; Rodents ; Shock ; Tularemia</subject><ispartof>Folia microbiologica, 1999-06, Vol.44 (3), p.306-310</ispartof><rights>Institute of Microbiology, Academy of Sciences of the Czech Republic 1999.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1357-d0af5f444ddab7ae4cc6aed47969ffb4086acb8eb2305307c453a490bc90293d3</citedby><cites>FETCH-LOGICAL-c1357-d0af5f444ddab7ae4cc6aed47969ffb4086acb8eb2305307c453a490bc90293d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>Stulík, J.</creatorcontrib><creatorcontrib>Hernychová, L.</creatorcontrib><creatorcontrib>Macela, A.</creatorcontrib><creatorcontrib>Kročová, Z.</creatorcontrib><creatorcontrib>Kroča, M.</creatorcontrib><title>Production of stress-inducible form of heat-shock protein 70 in mouse peritoneal adherent cells afterin Vivo infection byFrancisella tularensis</title><title>Folia microbiologica</title><description>Heat-shock proteins (hsp) are ubiquitously produced molecules which participate in the protection of cells from environmental perturbation. Moreover, the members of the heat-shock protein 60 (hsp60) and 70 (hsp70) families play an important role in pathogen-host interactions. We studiedin vivo production of the 70-kDa heat-shock proteins in the extract of peritoneal exudate cells (PEC) from mice injected intraperitoneally with an attenuated vaccine strain (LVS) ofFrancisella tularensis. We found a differential production of a highly stress-inducible member of the hsp70 family, designated hsp72, in three inbred strains of mice exhibiting either resistance or susceptibility toF. tularensis LVS infection. Whereas in tularemia-resistant mice hsp72 was even expressed in PEC without injection of bacteria and its production further increased on day 3 and slowly declined on days 5 and 7 after injection, in susceptible mice hsp72 production was highly inducble and restricted only to day 3 afterin vivo infection. Further analysis of hsp72 expression revealed intracellular hsp72 accumulation and its preferential production by peritoneal adherent cells.</description><subject>Adherent cells</subject><subject>Exudation</subject><subject>Heat</subject><subject>Heat shock proteins</subject><subject>Hsp60 protein</subject><subject>Hsp70 protein</subject><subject>Hsp72 protein</subject><subject>Inbreeding</subject><subject>Injection</subject><subject>Medical research</subject><subject>Peritoneal exudate cells</subject><subject>Peritoneum</subject><subject>Perturbation</subject><subject>Proteins</subject><subject>Rodents</subject><subject>Shock</subject><subject>Tularemia</subject><issn>0015-5632</issn><issn>1874-9356</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpdkU1r3DAQhkVJoJu0l_4CkUuh4HT0ZdnHNmTTwEJ7SHo1sjxilXqljSQH8ivyl6NlC4FcZmDeZz5ehpAvDC4ZgP7-cw28Y51S_ANZsU7LpheqPSErAKYa1Qr-kZzl_ADQghR8RV7-pDgttvgYaHQ0l4Q5Nz7Umh9npC6m3UHYoilN3kb7j-5TLOgD1UBr3MUlI91j8iUGNDM10xYThkItznOmxpWqBfrXP8XKOzzuGp_XyQTrc4UMLctsak_2-RM5dWbO-Pl_Pif36-u7q1_N5vfN7dWPTWOZULqZwDjlpJTTZEZtUFrbGpyk7tveuVFC1xo7djhyAUqAtlIJI3sYbQ-8F5M4J1-Pc6ubxwVzGXY-Hy42AaujoQPNteBMV_LiHfkQlxTqcYNWsmecMV6hb0fIpphzQjfsk9-Z9DwwGA6fGd4-I14BzkWDAA</recordid><startdate>19990601</startdate><enddate>19990601</enddate><creator>Stulík, J.</creator><creator>Hernychová, L.</creator><creator>Macela, A.</creator><creator>Kročová, Z.</creator><creator>Kroča, M.</creator><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope></search><sort><creationdate>19990601</creationdate><title>Production of stress-inducible form of heat-shock protein 70 in mouse peritoneal adherent cells afterin Vivo infection byFrancisella tularensis</title><author>Stulík, J. ; Hernychová, L. ; Macela, A. ; Kročová, Z. ; Kroča, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1357-d0af5f444ddab7ae4cc6aed47969ffb4086acb8eb2305307c453a490bc90293d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adherent cells</topic><topic>Exudation</topic><topic>Heat</topic><topic>Heat shock proteins</topic><topic>Hsp60 protein</topic><topic>Hsp70 protein</topic><topic>Hsp72 protein</topic><topic>Inbreeding</topic><topic>Injection</topic><topic>Medical research</topic><topic>Peritoneal exudate cells</topic><topic>Peritoneum</topic><topic>Perturbation</topic><topic>Proteins</topic><topic>Rodents</topic><topic>Shock</topic><topic>Tularemia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stulík, J.</creatorcontrib><creatorcontrib>Hernychová, L.</creatorcontrib><creatorcontrib>Macela, A.</creatorcontrib><creatorcontrib>Kročová, Z.</creatorcontrib><creatorcontrib>Kroča, M.</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><jtitle>Folia microbiologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stulík, J.</au><au>Hernychová, L.</au><au>Macela, A.</au><au>Kročová, Z.</au><au>Kroča, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Production of stress-inducible form of heat-shock protein 70 in mouse peritoneal adherent cells afterin Vivo infection byFrancisella tularensis</atitle><jtitle>Folia microbiologica</jtitle><date>1999-06-01</date><risdate>1999</risdate><volume>44</volume><issue>3</issue><spage>306</spage><epage>310</epage><pages>306-310</pages><issn>0015-5632</issn><eissn>1874-9356</eissn><abstract>Heat-shock proteins (hsp) are ubiquitously produced molecules which participate in the protection of cells from environmental perturbation. Moreover, the members of the heat-shock protein 60 (hsp60) and 70 (hsp70) families play an important role in pathogen-host interactions. We studiedin vivo production of the 70-kDa heat-shock proteins in the extract of peritoneal exudate cells (PEC) from mice injected intraperitoneally with an attenuated vaccine strain (LVS) ofFrancisella tularensis. We found a differential production of a highly stress-inducible member of the hsp70 family, designated hsp72, in three inbred strains of mice exhibiting either resistance or susceptibility toF. tularensis LVS infection. Whereas in tularemia-resistant mice hsp72 was even expressed in PEC without injection of bacteria and its production further increased on day 3 and slowly declined on days 5 and 7 after injection, in susceptible mice hsp72 production was highly inducble and restricted only to day 3 afterin vivo infection. Further analysis of hsp72 expression revealed intracellular hsp72 accumulation and its preferential production by peritoneal adherent cells.</abstract><cop>Dordrecht</cop><pub>Springer Nature B.V</pub><doi>10.1007/BF02818552</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0015-5632 |
| ispartof | Folia microbiologica, 1999-06, Vol.44 (3), p.306-310 |
| issn | 0015-5632 1874-9356 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_807273217 |
| source | Springer Nature - Complete Springer Journals |
| subjects | Adherent cells Exudation Heat Heat shock proteins Hsp60 protein Hsp70 protein Hsp72 protein Inbreeding Injection Medical research Peritoneal exudate cells Peritoneum Perturbation Proteins Rodents Shock Tularemia |
| title | Production of stress-inducible form of heat-shock protein 70 in mouse peritoneal adherent cells afterin Vivo infection byFrancisella tularensis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T16%3A43%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Production%20of%20stress-inducible%20form%20of%20heat-shock%20protein%2070%20in%20mouse%20peritoneal%20adherent%20cells%20afterin%20Vivo%20infection%20byFrancisella%20tularensis&rft.jtitle=Folia%20microbiologica&rft.au=Stul%C3%ADk,%20J.&rft.date=1999-06-01&rft.volume=44&rft.issue=3&rft.spage=306&rft.epage=310&rft.pages=306-310&rft.issn=0015-5632&rft.eissn=1874-9356&rft_id=info:doi/10.1007/BF02818552&rft_dat=%3Cproquest_cross%3E2146534611%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=754912112&rft_id=info:pmid/&rfr_iscdi=true |