Correlation between beta-2-glycoprotein I gene polymorphism and anti-beta-2 glycoprotein I antibodies in patients with multibacillary leprosy

Antiphospholipid antibodies, such as anti-β2-glycoprotein I (β2GPI), are present in multibacillary leprosy (MB) patients; however, MB patients do not usually present with antiphospholipid antibody syndrome (APS), which is characterized by thromboembolic phenomena (TEP). Rare cases of TEP occur in le...

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Veröffentlicht in:	Archives of Dermatological Research 2010-10, Vol.302 (8), p.583-591
Hauptverfasser:	Brochado, Maria José Franco, Figueiredo, José Fernando C, Mendes-Junior, Celso Teixeira, Louzada-Junior, Paulo, Kim, Olivia Makiyama, Roselino, Ana Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Antiphospholipid - blood Antiphospholipid antibodies Antiphospholipid antibody syndrome Bacterial diseases beta 2-Glycoprotein I - blood beta 2-Glycoprotein I - genetics beta 2-Glycoprotein I - immunology Beta-2-glycoprotein I Biological and medical sciences Blood and lymphatic vessels Brazil Cardiology. Vascular system Case-Control Studies Dermatology Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Enzyme-Linked Immunosorbent Assay Female Human bacterial diseases Humans Immunoglobulin G - blood Immunoglobulin G - immunology Immunoglobulin M - blood Immunoglobulin M - immunology Infectious diseases Leprosy Leprosy, Multibacillary - blood Leprosy, Multibacillary - genetics Leprosy, Multibacillary - immunology Leprosy, Paucibacillary - blood Leprosy, Paucibacillary - genetics Leprosy, Paucibacillary - immunology Male Medical sciences Medicine Medicine & Public Health Middle Aged Original Paper Point Mutation Polymerase Chain Reaction Polymorphism genetic Polymorphism, Single Nucleotide Thromboembolic phenomena Tropical bacterial diseases
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