Calcium-containing mitochondrial granules in neurohypophysial axon terminals disappear following vasopressin treatment of brattleboro rats
The presence of intramitochondrial calcium-containing electron-dense granules was demonstrated in axon terminals of chronically hyperactive neurosecretory neurons of untreated homozygous Brattleboro rats. Following vasopressin treatment for 30 days, which has been shown to attenuate this neuronal hy...
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| Veröffentlicht in: | Neuroscience letters 1983-08, Vol.39 (2), p.181-185 |
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| container_title | Neuroscience letters |
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| creator | KARCSU, S LASZLO, F. A TOTH, L JANCSO, G BACSY, E |
| description | The presence of intramitochondrial calcium-containing electron-dense granules was demonstrated in axon terminals of chronically hyperactive neurosecretory neurons of untreated homozygous Brattleboro rats. Following vasopressin treatment for 30 days, which has been shown to attenuate this neuronal hyperactivity, calcium-containing deposits could not be detected in mitochondria. It is concluded that the presence of intramitochondrial calcium-containing dense deposits is connected with the functional state of neurosecretory neurons. |
| doi_str_mv | 10.1016/0304-3940(83)90074-5 |
| format | Article |
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It is concluded that the presence of intramitochondrial calcium-containing dense deposits is connected with the functional state of neurosecretory neurons.</description><identifier>ISSN: 0304-3940</identifier><identifier>EISSN: 1872-7972</identifier><identifier>DOI: 10.1016/0304-3940(83)90074-5</identifier><identifier>PMID: 6633949</identifier><identifier>CODEN: NELED5</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Animals ; Axons - physiology ; Biological and medical sciences ; Brattleboro rat ; calcium ; Calcium - physiology ; cytochemistry ; Cytoplasmic Granules - physiology ; Cytoplasmic Granules - ultrastructure ; Fundamental and applied biological sciences. Psychology ; Hormones and neuropeptides. Regulation ; Hypothalamus. Hypophysis. Epiphysis. Urophysis ; Mitochondria - physiology ; Mitochondria - ultrastructure ; Nerve Endings - physiology ; neurohypophysis ; neuronal activity ; Pituitary Gland, Posterior - physiology ; Pituitary Gland, Posterior - ultrastructure ; Rats ; Rats, Brattleboro - physiology ; Rats, Mutant Strains - physiology ; vasopressin treatment ; Vasopressins - pharmacology ; Vertebrates: endocrinology ; X-ray microanalysis</subject><ispartof>Neuroscience letters, 1983-08, Vol.39 (2), p.181-185</ispartof><rights>1983</rights><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c332t-329bb39b392487ae7b9fbfcc6b5bc7f70a54dc154232b948296d1336fa7b09c23</citedby><cites>FETCH-LOGICAL-c332t-329bb39b392487ae7b9fbfcc6b5bc7f70a54dc154232b948296d1336fa7b09c23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0304-3940(83)90074-5$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9420058$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6633949$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KARCSU, S</creatorcontrib><creatorcontrib>LASZLO, F. A</creatorcontrib><creatorcontrib>TOTH, L</creatorcontrib><creatorcontrib>JANCSO, G</creatorcontrib><creatorcontrib>BACSY, E</creatorcontrib><title>Calcium-containing mitochondrial granules in neurohypophysial axon terminals disappear following vasopressin treatment of brattleboro rats</title><title>Neuroscience letters</title><addtitle>Neurosci Lett</addtitle><description>The presence of intramitochondrial calcium-containing electron-dense granules was demonstrated in axon terminals of chronically hyperactive neurosecretory neurons of untreated homozygous Brattleboro rats. Following vasopressin treatment for 30 days, which has been shown to attenuate this neuronal hyperactivity, calcium-containing deposits could not be detected in mitochondria. It is concluded that the presence of intramitochondrial calcium-containing dense deposits is connected with the functional state of neurosecretory neurons.</description><subject>Animals</subject><subject>Axons - physiology</subject><subject>Biological and medical sciences</subject><subject>Brattleboro rat</subject><subject>calcium</subject><subject>Calcium - physiology</subject><subject>cytochemistry</subject><subject>Cytoplasmic Granules - physiology</subject><subject>Cytoplasmic Granules - ultrastructure</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hormones and neuropeptides. Regulation</subject><subject>Hypothalamus. Hypophysis. Epiphysis. Urophysis</subject><subject>Mitochondria - physiology</subject><subject>Mitochondria - ultrastructure</subject><subject>Nerve Endings - physiology</subject><subject>neurohypophysis</subject><subject>neuronal activity</subject><subject>Pituitary Gland, Posterior - physiology</subject><subject>Pituitary Gland, Posterior - ultrastructure</subject><subject>Rats</subject><subject>Rats, Brattleboro - physiology</subject><subject>Rats, Mutant Strains - physiology</subject><subject>vasopressin treatment</subject><subject>Vasopressins - pharmacology</subject><subject>Vertebrates: endocrinology</subject><subject>X-ray microanalysis</subject><issn>0304-3940</issn><issn>1872-7972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU2r1DAUhoMo1_HqP1DIQkQX1Xy0TbMRZPALLrjRdUjS0zuRNKlJenX-gr_a1BlmqRBIyHnOy0kehJ5S8poS2r8hnLQNly15OfBXkhDRNt09tKODYI2Qgt1HuwvyED3K-TshpKNde4Wu-p7Xa7lDv_faW7fOjY2haBdcuMWzK9EeYhiT0x7fJh1WDxm7gAOsKR6OS1wOx7wV9a8YcIE0u6B9xqPLellAJzxF7-PPLe1O57gkyLn2lwS6zBAKjhM2SZfiwcQUcT3mx-jBVEPgyXm_Rt8-vP-6_9TcfPn4ef_uprGcs9JwJo3hsi7WDkKDMHIyk7W96YwVkyC6a0dbn8k4M7IdmOxHynk_aWGItIxfoxen3CXFHyvkomaXLXivA8Q1q4EIxkkn_gtSLojsKa1gewJtijknmNSS3KzTUVGiNldqE6E2EWrg6q8r1dW2Z-f81cwwXprOcmr9-bmus9V-qiKsyxdMtqz6HCr29oRB_bQ7B0ll6yBYGF0CW9QY3b_n-AO3hbQq</recordid><startdate>19830829</startdate><enddate>19830829</enddate><creator>KARCSU, S</creator><creator>LASZLO, F. A</creator><creator>TOTH, L</creator><creator>JANCSO, G</creator><creator>BACSY, E</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19830829</creationdate><title>Calcium-containing mitochondrial granules in neurohypophysial axon terminals disappear following vasopressin treatment of brattleboro rats</title><author>KARCSU, S ; LASZLO, F. A ; TOTH, L ; JANCSO, G ; BACSY, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c332t-329bb39b392487ae7b9fbfcc6b5bc7f70a54dc154232b948296d1336fa7b09c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Animals</topic><topic>Axons - physiology</topic><topic>Biological and medical sciences</topic><topic>Brattleboro rat</topic><topic>calcium</topic><topic>Calcium - physiology</topic><topic>cytochemistry</topic><topic>Cytoplasmic Granules - physiology</topic><topic>Cytoplasmic Granules - ultrastructure</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hormones and neuropeptides. Regulation</topic><topic>Hypothalamus. Hypophysis. Epiphysis. Urophysis</topic><topic>Mitochondria - physiology</topic><topic>Mitochondria - ultrastructure</topic><topic>Nerve Endings - physiology</topic><topic>neurohypophysis</topic><topic>neuronal activity</topic><topic>Pituitary Gland, Posterior - physiology</topic><topic>Pituitary Gland, Posterior - ultrastructure</topic><topic>Rats</topic><topic>Rats, Brattleboro - physiology</topic><topic>Rats, Mutant Strains - physiology</topic><topic>vasopressin treatment</topic><topic>Vasopressins - pharmacology</topic><topic>Vertebrates: endocrinology</topic><topic>X-ray microanalysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KARCSU, S</creatorcontrib><creatorcontrib>LASZLO, F. A</creatorcontrib><creatorcontrib>TOTH, L</creatorcontrib><creatorcontrib>JANCSO, G</creatorcontrib><creatorcontrib>BACSY, E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KARCSU, S</au><au>LASZLO, F. A</au><au>TOTH, L</au><au>JANCSO, G</au><au>BACSY, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Calcium-containing mitochondrial granules in neurohypophysial axon terminals disappear following vasopressin treatment of brattleboro rats</atitle><jtitle>Neuroscience letters</jtitle><addtitle>Neurosci Lett</addtitle><date>1983-08-29</date><risdate>1983</risdate><volume>39</volume><issue>2</issue><spage>181</spage><epage>185</epage><pages>181-185</pages><issn>0304-3940</issn><eissn>1872-7972</eissn><coden>NELED5</coden><abstract>The presence of intramitochondrial calcium-containing electron-dense granules was demonstrated in axon terminals of chronically hyperactive neurosecretory neurons of untreated homozygous Brattleboro rats. Following vasopressin treatment for 30 days, which has been shown to attenuate this neuronal hyperactivity, calcium-containing deposits could not be detected in mitochondria. It is concluded that the presence of intramitochondrial calcium-containing dense deposits is connected with the functional state of neurosecretory neurons.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>6633949</pmid><doi>10.1016/0304-3940(83)90074-5</doi><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 0304-3940 |
| ispartof | Neuroscience letters, 1983-08, Vol.39 (2), p.181-185 |
| issn | 0304-3940 1872-7972 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Axons - physiology Biological and medical sciences Brattleboro rat calcium Calcium - physiology cytochemistry Cytoplasmic Granules - physiology Cytoplasmic Granules - ultrastructure Fundamental and applied biological sciences. Psychology Hormones and neuropeptides. Regulation Hypothalamus. Hypophysis. Epiphysis. Urophysis Mitochondria - physiology Mitochondria - ultrastructure Nerve Endings - physiology neurohypophysis neuronal activity Pituitary Gland, Posterior - physiology Pituitary Gland, Posterior - ultrastructure Rats Rats, Brattleboro - physiology Rats, Mutant Strains - physiology vasopressin treatment Vasopressins - pharmacology Vertebrates: endocrinology X-ray microanalysis |
| title | Calcium-containing mitochondrial granules in neurohypophysial axon terminals disappear following vasopressin treatment of brattleboro rats |
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