Influence of β-lactamase- producing strains of Branhamella catarrhalis and Haemophilus influenzae on certain β-lactam antibiotics

Ampicillin, benzylpenicillin, cefaclor and cefuroxime were exposed to strains of Branhamella catarrhalis and Haemophilus influenzae with and without ability to produce β-lactamase. The antibiotics were dissolved in phosphate buffer at pH 6, 7 and 8 and the mean enzyme activity was calculated from de...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 1983-09, Vol.12 (3), p.269-271
Hauptverfasser:	Johnsson, Jan, Brorson, John- Erik
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - metabolism beta-Lactamases - pharmacology beta-Lactams Branhamella catarrhalis Drug Stability Haemophilus influenzae Haemophilus influenzae - enzymology Hydrogen-Ion Concentration Hydrolysis Neisseriaceae - enzymology
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