Hysterosalpingography with oil contrast medium enhances fertility in patients with infertility of unknown etiology
Previous studies have suggested increased fertility rates following hysterosalpingography (HSG) using oil as compared with aqueous contrast medium. To compare the possible fertility-enhancing effects of two agents used for HSG, this prospective randomized study evaluated the subsequent fertility rat...
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| Veröffentlicht in: | Fertility and sterility 1983-11, Vol.40 (5), p.604-606 |
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| container_title | Fertility and sterility |
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| creator | Schwabe, Mark G. Shapiro, Sander S. Haning, Ray V. |
| description | Previous studies have suggested increased fertility rates following hysterosalpingography (HSG) using oil as compared with aqueous contrast medium. To compare the possible fertility-enhancing effects of two agents used for HSG, this prospective randomized study evaluated the subsequent fertility rates in 121 patients who underwent HSG, in which either oil or aqueous contrast medium was used. After random assignment to either agent, patients were observed for four menstrual cycles after HSG without resorting to any therapy other than clomiphene citrate where indicated. The pregnancy rates for the four cycles after HSG were compared with chisquare analysis in the total study and in the diagnostic subgroups. The subgroup with infertility of unknown cause had a significantly higher pregnancy rate after HSG with oil than after HSG with aqueous contrast medium. No significant difference was seen for any other subgroup or for the overall cohort. |
| doi_str_mv | 10.1016/S0015-0282(16)47417-0 |
| format | Article |
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To compare the possible fertility-enhancing effects of two agents used for HSG, this prospective randomized study evaluated the subsequent fertility rates in 121 patients who underwent HSG, in which either oil or aqueous contrast medium was used. After random assignment to either agent, patients were observed for four menstrual cycles after HSG without resorting to any therapy other than clomiphene citrate where indicated. The pregnancy rates for the four cycles after HSG were compared with chisquare analysis in the total study and in the diagnostic subgroups. The subgroup with infertility of unknown cause had a significantly higher pregnancy rate after HSG with oil than after HSG with aqueous contrast medium. 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To compare the possible fertility-enhancing effects of two agents used for HSG, this prospective randomized study evaluated the subsequent fertility rates in 121 patients who underwent HSG, in which either oil or aqueous contrast medium was used. After random assignment to either agent, patients were observed for four menstrual cycles after HSG without resorting to any therapy other than clomiphene citrate where indicated. The pregnancy rates for the four cycles after HSG were compared with chisquare analysis in the total study and in the diagnostic subgroups. The subgroup with infertility of unknown cause had a significantly higher pregnancy rate after HSG with oil than after HSG with aqueous contrast medium. No significant difference was seen for any other subgroup or for the overall cohort.</description><subject>Biological and medical sciences</subject><subject>Birth control</subject><subject>Contrast Media - administration & dosage</subject><subject>Diatrizoate Meglumine - administration & dosage</subject><subject>Drug Evaluation</subject><subject>Ethiodized Oil - administration & dosage</subject><subject>Female</subject><subject>Fertility - drug effects</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Hysterosalpingography</subject><subject>Infertility, Female - diagnostic imaging</subject><subject>Infertility, Female - etiology</subject><subject>Medical sciences</subject><subject>Pregnancy - drug effects</subject><subject>Probability</subject><subject>Random Allocation</subject><subject>Sterility. 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Assisted procreation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schwabe, Mark G.</creatorcontrib><creatorcontrib>Shapiro, Sander S.</creatorcontrib><creatorcontrib>Haning, Ray V.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schwabe, Mark G.</au><au>Shapiro, Sander S.</au><au>Haning, Ray V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hysterosalpingography with oil contrast medium enhances fertility in patients with infertility of unknown etiology</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>1983-11</date><risdate>1983</risdate><volume>40</volume><issue>5</issue><spage>604</spage><epage>606</epage><pages>604-606</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><coden>FESTAS</coden><abstract>Previous studies have suggested increased fertility rates following hysterosalpingography (HSG) using oil as compared with aqueous contrast medium. To compare the possible fertility-enhancing effects of two agents used for HSG, this prospective randomized study evaluated the subsequent fertility rates in 121 patients who underwent HSG, in which either oil or aqueous contrast medium was used. After random assignment to either agent, patients were observed for four menstrual cycles after HSG without resorting to any therapy other than clomiphene citrate where indicated. The pregnancy rates for the four cycles after HSG were compared with chisquare analysis in the total study and in the diagnostic subgroups. The subgroup with infertility of unknown cause had a significantly higher pregnancy rate after HSG with oil than after HSG with aqueous contrast medium. No significant difference was seen for any other subgroup or for the overall cohort.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>6313436</pmid><doi>10.1016/S0015-0282(16)47417-0</doi><tpages>3</tpages></addata></record> |
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| identifier | ISSN: 0015-0282 |
| ispartof | Fertility and sterility, 1983-11, Vol.40 (5), p.604-606 |
| issn | 0015-0282 1556-5653 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80703191 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Biological and medical sciences Birth control Contrast Media - administration & dosage Diatrizoate Meglumine - administration & dosage Drug Evaluation Ethiodized Oil - administration & dosage Female Fertility - drug effects Gynecology. Andrology. Obstetrics Humans Hysterosalpingography Infertility, Female - diagnostic imaging Infertility, Female - etiology Medical sciences Pregnancy - drug effects Probability Random Allocation Sterility. Assisted procreation |
| title | Hysterosalpingography with oil contrast medium enhances fertility in patients with infertility of unknown etiology |
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