Impaired coronary flow and ventricular function in hearts of hypertensive rats

Hearts of rats made hypertensive (BP> 150 mmHg) by left renal artery clipping and sham operated controls were studied in two series of experiments. In series I, cardiac function was studied in an isolated working heart apparatus at weeks 4, 9 to 10 and 16 to 17 post-surgery. In series II, coronar...

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Veröffentlicht in:	Cardiovascular research 1983-09, Vol.17 (9), p.553-561
Hauptverfasser:	ALFARO, ABRAHAM, SCHAIBLE, THOMAS F, MALHOTRA, ASHWANI, YIPINTSOI, TADA, SCHEUER, JAMES
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system contractility Coronary Circulation diastolic compliance Experimental diseases Heart - physiopathology Heart Ventricles - physiopathology Hypertension - metabolism Hypertension - physiopathology hypoxia Hypoxia - physiopathology ischaemia Lactates - metabolism Male Medical sciences myocardial metabolism Myocardium - metabolism Oxygen Consumption Perfusion Pyruvates - metabolism Rats Rats, Inbred Strains Space life sciences
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