Decreased macrophage-mediated suppression of lymphocyte activation in chronic renal failure

Prostaglandin-dependent adherent cell suppressor activity was assessed in patients with end-stage renal insufficiency. Proliferative responses of uremic peripheral blood mononuclear cells to optimal concentrations of phytohemagglutinin and concanavalin A were impaired. Responses to the galactosyl-di...

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Veröffentlicht in:	The American journal of medicine 1983-01, Vol.75 (4), p.571-579
Hauptverfasser:	Ruddy, Michael C., Rubin, Albert L., Novogrodsky, Abraham, Stenzel, Kurt H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alprostadil Biological and medical sciences Blastomeres - immunology Cyclic AMP - immunology Female Humans Immunity, Cellular Indomethacin - pharmacology Kidney Failure, Chronic - immunology Lymphocyte Activation Macrophages - immunology Male Medical sciences Middle Aged Mitogens - immunology Monocytes - immunology Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Prostaglandins E - immunology Renal failure
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