A kinetic model for the alpha-thrombin-catalyzed conversion of plasma levels of fibrinogen to fibrin in the presence of antithrombin III

In this study we report a kinetic model for the alpha-thrombin-catalyzed production of fibrin I and fibrin II at pH 7.4, 37 degrees C, gamma/2 0.17. The fibrin is produced by the action of human alpha-thrombin on plasma levels of human fibrinogen in the presence of the major inhibitor of alpha-throm...

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Veröffentlicht in:	The Journal of biological chemistry 1991-07, Vol.266 (20), p.13003-13010
Hauptverfasser:	NASKI, M. C, SHAFER, J. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antithrombin III - pharmacology Biological and medical sciences Blood coagulation. Blood cells fibrin Fibrin - metabolism fibrinogen Fibrinogen - metabolism Fibrinopeptide B - isolation & purification Fibrinopeptide B - metabolism Fundamental and applied biological sciences. Psychology General aspects, investigation methods, hemostasis, fibrinolysis Humans Kinetics Mathematics Models, Theoretical Molecular and cellular biology Thrombin - metabolism
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