Comparison of Cross-Reactivities of Imipenem and Other Beta-Lactam Antibiotics by Delayed-Type Hypersensitivity Reaction in Guinea Pigs

The cross-reactivity of imipenem (IPM) in a delayed-type hypersensitivity (DTH) reaction was investigated by intradermal skin reaction, macrophage migration inhibition tests (MIT) and lymphocyte stimulation tests (LST) in guinea pigs. The animals were immunized with IPM, ampicillin (ABPC) or cephale...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 1991/03/25, Vol.39(3), pp.765-768
Hauptverfasser:	NAGAKURA, Naoki, SOUMA, Shinji, SHIMIZU, Tadayori, UNO, Katsuji, YANAGIHARA, Yasutake
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - immunology Antibiotics. Antiinfectious agents. Antiparasitic agents beta-lactam Biological and medical sciences Cross Reactions - immunology delayed-type hypersensitivity Drug Hypersensitivity - immunology guinea pig Guinea Pigs Hypersensitivity, Delayed - immunology imipenem Imipenem - immunology intradermal skin test lymphocyte stimulation test macrophage migration inhibition test Male Medical sciences Pharmacology. Drug treatments
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