HLA‐class‐I and‐class‐II expression on renal tumor xenografts and the relation to sensitivity for α‐IFN, γ‐IFN and TNF

In this study we evaluated the usefulness of the histocom‐patibility leucocyte antigen (HLA) class‐I and class‐II expression on renal‐cell carcinoma (RCC) xenografts as predictive markers for response to cytokine therapy. Eight different RCC xenografts growing in BALBC nu/nu mice were treated with 0...

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Veröffentlicht in:	International journal of cancer 1991-07, Vol.48 (5), p.709-716
Hauptverfasser:	Beniers, A. J. M. C., Peelen, W. P., Debruyne, F. M. J., Schalken, J. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Carcinoma, Renal Cell - immunology Carcinoma, Renal Cell - pathology Cell Line Female Gene Expression - drug effects Genes, MHC Class I - drug effects Genes, MHC Class II - drug effects Histocompatibility Antigens Class I - analysis Histocompatibility Antigens Class II - analysis Humans Immunotherapy Interferon Type I - pharmacology Interferon-gamma - pharmacology Kidney Neoplasms - immunology Kidney Neoplasms - pathology Male Medical sciences Mice Mice, Nude Neoplasm Transplantation Pharmacology. Drug treatments Recombinant Proteins - pharmacology Transplantation, Heterologous Tumor Necrosis Factor-alpha - pharmacology
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