Pertussis toxin pretreatment affects opiate/nonopiate and stress-induced analgesia differently

Intracerebroventricular injection of pertussis toxin (PTX, 1 μg/rat) six days before the hot plate test abolished analgesia induced by central morphine. The toxin did not affect analgesia evoked by central neurotensin or ASU 1–7 eel calcitonin. PTX pretreatment also attenuated footshock-induced anal...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1991-03, Vol.38 (3), p.569-573
Hauptverfasser:	Parolaro, Daniela, Massi, Paola, Patrini, Gabriela, Rubino, Tiziana, Parenti, Marco, Gori, Enzo
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesia Animals ASU 1–7 eel calcitonin Calcitonin - analogs & derivatives Calcitonin - antagonists & inhibitors Electroshock Foot shock-induced analgesia Injections, Intraventricular Male Microinjections Morphine - antagonists & inhibitors Neurotensin Neurotensin - antagonists & inhibitors Pain - physiopathology Pain Measurement Pertussis Toxin Rats Rats, Inbred Strains Stress, Physiological - physiopathology Time Factors Virulence Factors, Bordetella - pharmacology
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