Sterol carrier protein2. Identification of adrenal sterol carrier protein2 and site of action for mitochondrial cholesterol utilization

Addition of homogeneous rat liver sterol carrier protein2 (SCP2) or an adrenal cytosolic fraction enhanced pregnenolone production by adrenal mitochondria. Pretreatment of SCP2 or adrenal cytosol with anti-SCP2 IgG abolished the stimulatory effect of both preparations on mitochondrial pregnenolone o...

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Veröffentlicht in:	The Journal of biological chemistry 1983-10, Vol.258 (19), p.11731-11737
Hauptverfasser:	Vahouny, G V, Chanderbhan, R, Noland, B J, Irwin, D, Dennis, P, Lambeth, J D, Scallen, T J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Glands - metabolism Adrenocorticotropic Hormone - pharmacology Animals Biological and medical sciences Carrier Proteins - isolation & purification Carrier Proteins - metabolism Cell structures and functions Cholesterol - metabolism Cycloheximide - pharmacology Cytosol - metabolism Electrophoresis, Polyacrylamide Gel Fundamental and applied biological sciences. Psychology Immunoelectrophoresis Kinetics Liver - metabolism Male Microsomes, Liver - metabolism Mitochondria - drug effects Mitochondria - metabolism Mitochondria and cell respiration Molecular and cellular biology Plant Proteins Pregnenolone - biosynthesis Rats Rats, Inbred Strains Sterols - metabolism
Online-Zugang:	Volltext
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