D1/D2 dopamine receptor stimulation by L-DOPA : a [14C]-2-deoxyglucose autoradiographic study

In rats with unilateral 6-hydroxydopamine substantia nigra lesions, the effects of selective D1 and D2 dopamine receptor antagonists on L-DOPA-induced rotation and regional cerebral glucose utilization (RCGU) changes were examined. Contralateral rotation induced by L-DOPA (25 mg/kg) was effectively...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 1991-06, Vol.114 (3), p.1429-1440
Hauptverfasser:	TRUGMAN, J. M, JAMES, C. L, WOOTEN, G. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoradiography Benzazepines - pharmacology Biological and medical sciences Biological Transport, Active - drug effects Brain - drug effects Brain - metabolism Carbon Radioisotopes Deoxyglucose - metabolism Glucose - metabolism Levodopa - pharmacology Male Medical sciences Models, Neurological Motor Activity - drug effects Neuropharmacology Pharmacology. Drug treatments Rats Rats, Inbred Strains Receptors, Dopamine - drug effects Receptors, Dopamine - physiology Receptors, Dopamine D1 Receptors, Dopamine D2 Salicylamides - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!