The role of PGE2 in the sensitization of mechanoreceptors in normal and inflamed ankle joints of the rat

The role of PGE2 in the sensitization of high-threshold tarsal joint mechanoreceptors (putative nociceptors) has been investigated in 11 arthritic and 16 normal rats. Injections of a low dose of Freund's complete adjuvant at multiple sites into the tissues surrounding the ankle joint induced a...

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Veröffentlicht in:	Experimental brain research 1991-01, Vol.84 (2), p.383-392
Hauptverfasser:	GRUBB, B. D, BIRRELL, G. J, MCQUEEN, D. S, IGGO, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Animals Arthritis, Experimental - physiopathology Biological and medical sciences Bradykinin - pharmacology Dinoprostone - pharmacology Dinoprostone - physiology Electric Stimulation - methods Freund's Adjuvant Fundamental and applied biological sciences. Psychology Inflammation Joints - physiology Joints - physiopathology Male Mechanoreceptors - drug effects Mechanoreceptors - physiology Molecular and cellular biology Rats Rats, Inbred Strains Reference Values Space life sciences
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