Differing characteristics of human papillomavirus rna‐positive and rna‐negative anal carcinomas

Anal carcinomas were tested for the presence of human papillomavirus (HPV) RNA transcripts by in situ hybridization using 125I‐labeled RNA probes. The HPV transcripts were detected in 73.2% of 41 nonglandular anal carcinomas but in none of six anal or 11 rectal adenocarcinomas. In anal nonglandular...

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Veröffentlicht in:	Cancer 1991-08, Vol.68 (3), p.561-567
Hauptverfasser:	Higgins, Geoffrey D., Uzelin, Diana M., Burrell, Christopher J., Phillips, Gael E., Pieterse, Arnoldus S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - microbiology Aged Anus Neoplasms - microbiology Anus Neoplasms - pathology Carcinoma, Squamous Cell - microbiology Carcinoma, Squamous Cell - pathology Carcinoma, Transitional Cell - metabolism Carcinoma, Transitional Cell - pathology Epithelium - pathology Female Humans Male Middle Aged Neoplasm Invasiveness Nucleic Acid Hybridization Papillomaviridae - genetics Rectal Neoplasms - microbiology RNA Probes RNA, Viral - analysis Tumor Virus Infections
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