Computer-assisted image analysis of skin surface replicas
Summary Using a rubber‐based dental impression material, negative surface impressions were made of demarcated areas of skin and prepared as dry specimens for scanning‐electron microscopy. Electron micrographs were taken at low magnification and, using a programed computer‐assisted image analyser, it...
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| Veröffentlicht in: | British journal of dermatology (1951) 1991-06, Vol.124 (6), p.571-575 |
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| container_issue | 6 |
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| container_title | British journal of dermatology (1951) |
| container_volume | 124 |
| creator | MURPHY, RUTH COTTON, D. W. K. WRIGHT, A. L. BLEEHEN, S. S. |
| description | Summary
Using a rubber‐based dental impression material, negative surface impressions were made of demarcated areas of skin and prepared as dry specimens for scanning‐electron microscopy. Electron micrographs were taken at low magnification and, using a programed computer‐assisted image analyser, it was possible to represent quantitatively the topography of that particular body site according to the degree of circularity of the various geometric subunits. This technique was most applicable to skin topography with a reliable geometrical pattern of triangles and squares, a feature of hair‐bearing surfaces in general and in particular, the antecubital fossa. Using standardized trauma of various types the origin of skin surface markings were found to be located in the dermis. The technique was applied to the healing of experimental trauma produced by tape stripping, the resolution of clinical eczema and a comparison of steroid‐treated and untreated tape‐stripped skin. |
| doi_str_mv | 10.1111/j.1365-2133.1991.tb04953.x |
| format | Article |
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Using a rubber‐based dental impression material, negative surface impressions were made of demarcated areas of skin and prepared as dry specimens for scanning‐electron microscopy. Electron micrographs were taken at low magnification and, using a programed computer‐assisted image analyser, it was possible to represent quantitatively the topography of that particular body site according to the degree of circularity of the various geometric subunits. This technique was most applicable to skin topography with a reliable geometrical pattern of triangles and squares, a feature of hair‐bearing surfaces in general and in particular, the antecubital fossa. Using standardized trauma of various types the origin of skin surface markings were found to be located in the dermis. The technique was applied to the healing of experimental trauma produced by tape stripping, the resolution of clinical eczema and a comparison of steroid‐treated and untreated tape‐stripped skin.</description><identifier>ISSN: 0007-0963</identifier><identifier>EISSN: 1365-2133</identifier><identifier>DOI: 10.1111/j.1365-2133.1991.tb04953.x</identifier><identifier>PMID: 2064941</identifier><identifier>CODEN: BJDEAZ</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Biological and medical sciences ; Dermatology ; Eczema - pathology ; Humans ; Image Processing, Computer-Assisted - methods ; Investigative techniques, diagnostic techniques (general aspects) ; Medical sciences ; Microscopy, Electron, Scanning ; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques ; Skin - ultrastructure ; Surface Properties</subject><ispartof>British journal of dermatology (1951), 1991-06, Vol.124 (6), p.571-575</ispartof><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5321-d42b19bd8cc4eec4837b0becd40d28970d336b0fa2626107e6987e2a476c16e83</citedby><cites>FETCH-LOGICAL-c5321-d42b19bd8cc4eec4837b0becd40d28970d336b0fa2626107e6987e2a476c16e83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2133.1991.tb04953.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2133.1991.tb04953.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,782,786,1419,27931,27932,45581,45582</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19713840$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2064941$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MURPHY, RUTH</creatorcontrib><creatorcontrib>COTTON, D. W. K.</creatorcontrib><creatorcontrib>WRIGHT, A. L.</creatorcontrib><creatorcontrib>BLEEHEN, S. S.</creatorcontrib><title>Computer-assisted image analysis of skin surface replicas</title><title>British journal of dermatology (1951)</title><addtitle>Br J Dermatol</addtitle><description>Summary
Using a rubber‐based dental impression material, negative surface impressions were made of demarcated areas of skin and prepared as dry specimens for scanning‐electron microscopy. Electron micrographs were taken at low magnification and, using a programed computer‐assisted image analyser, it was possible to represent quantitatively the topography of that particular body site according to the degree of circularity of the various geometric subunits. This technique was most applicable to skin topography with a reliable geometrical pattern of triangles and squares, a feature of hair‐bearing surfaces in general and in particular, the antecubital fossa. Using standardized trauma of various types the origin of skin surface markings were found to be located in the dermis. The technique was applied to the healing of experimental trauma produced by tape stripping, the resolution of clinical eczema and a comparison of steroid‐treated and untreated tape‐stripped skin.</description><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Eczema - pathology</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted - methods</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Microscopy, Electron, Scanning</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</subject><subject>Skin - ultrastructure</subject><subject>Surface Properties</subject><issn>0007-0963</issn><issn>1365-2133</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkUtLxDAUhYMoOj5-glAE3bXeNGnSuBC0vhl0owhuQpreSsfOdEymOPPvbZkyrs0mkHPuOckXQk4oRLRb55OIMpGEMWUsokrRaJEDVwmLlltktJG2yQgAZAhKsD2y7_0EgDJIYJfsxiC44nREVNZM5-0CXWi8r_wCi6Camk8MzMzUq-4kaMrAf1WzwLeuNBYDh_O6ssYfkp3S1B6Phv2AvN3dvmYP4fjl_jG7Goc2YTENCx7nVOVFai1HtDxlMoccbcGhiFMloWBM5FCaWMSCgkShUomx4VJYKjBlB-RsnTt3zXeLfqGnlbdY12aGTet1CkIATURnvFgbrWu8d1jqueve4laagu656Ynu4egeju656YGbXnbDx0NLm0-x2IwOoDr9dNCNt6YunZnZyv81KElZyqHzXa59P1WNq3_cQF8_3SSyLwrXAf1nLDcBxn1pIZlM9PvzvR5nEuAj4_qa_QItZJhQ</recordid><startdate>199106</startdate><enddate>199106</enddate><creator>MURPHY, RUTH</creator><creator>COTTON, D. W. K.</creator><creator>WRIGHT, A. L.</creator><creator>BLEEHEN, S. S.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199106</creationdate><title>Computer-assisted image analysis of skin surface replicas</title><author>MURPHY, RUTH ; COTTON, D. W. K. ; WRIGHT, A. L. ; BLEEHEN, S. S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5321-d42b19bd8cc4eec4837b0becd40d28970d336b0fa2626107e6987e2a476c16e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Eczema - pathology</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted - methods</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Medical sciences</topic><topic>Microscopy, Electron, Scanning</topic><topic>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</topic><topic>Skin - ultrastructure</topic><topic>Surface Properties</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MURPHY, RUTH</creatorcontrib><creatorcontrib>COTTON, D. W. K.</creatorcontrib><creatorcontrib>WRIGHT, A. L.</creatorcontrib><creatorcontrib>BLEEHEN, S. S.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of dermatology (1951)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MURPHY, RUTH</au><au>COTTON, D. W. K.</au><au>WRIGHT, A. L.</au><au>BLEEHEN, S. S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Computer-assisted image analysis of skin surface replicas</atitle><jtitle>British journal of dermatology (1951)</jtitle><addtitle>Br J Dermatol</addtitle><date>1991-06</date><risdate>1991</risdate><volume>124</volume><issue>6</issue><spage>571</spage><epage>575</epage><pages>571-575</pages><issn>0007-0963</issn><eissn>1365-2133</eissn><coden>BJDEAZ</coden><abstract>Summary
Using a rubber‐based dental impression material, negative surface impressions were made of demarcated areas of skin and prepared as dry specimens for scanning‐electron microscopy. Electron micrographs were taken at low magnification and, using a programed computer‐assisted image analyser, it was possible to represent quantitatively the topography of that particular body site according to the degree of circularity of the various geometric subunits. This technique was most applicable to skin topography with a reliable geometrical pattern of triangles and squares, a feature of hair‐bearing surfaces in general and in particular, the antecubital fossa. Using standardized trauma of various types the origin of skin surface markings were found to be located in the dermis. The technique was applied to the healing of experimental trauma produced by tape stripping, the resolution of clinical eczema and a comparison of steroid‐treated and untreated tape‐stripped skin.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>2064941</pmid><doi>10.1111/j.1365-2133.1991.tb04953.x</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-0963 |
| ispartof | British journal of dermatology (1951), 1991-06, Vol.124 (6), p.571-575 |
| issn | 0007-0963 1365-2133 |
| language | eng |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | Biological and medical sciences Dermatology Eczema - pathology Humans Image Processing, Computer-Assisted - methods Investigative techniques, diagnostic techniques (general aspects) Medical sciences Microscopy, Electron, Scanning Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Skin - ultrastructure Surface Properties |
| title | Computer-assisted image analysis of skin surface replicas |
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