In vivo prevalence of azidothymidine (AZT) resistance mutations in an AIDS patient before and after AZT therapy

In order to examine the in vivo prevalence of AZT resistance mutations in AID patients after long-term therapy we amplified, by polymerase chain reaction (PCR), a 654 bp pol gene fragment from peripheral blood mononuclear cell DNA samples from a patient before, and 19 months after, the start of AZT...

Ausführliche Beschreibung