Plasma membrane lipid structural order in doxorubicin-sensitive and -resistant P388 cells

We have studied the structural order of the lipid phase of plasma membranes from P388 murine leukemia cells and from a Doxorubicin-resistant subline, P388/ADR, using electron spin resonance spectroscopy and fluorescence depolarization measurements. Measurements of the order parameter, S, following i...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1983-11, Vol.43 (11), p.5533-5537
Hauptverfasser:	RAMU, A, GLAUBIGER, D, MAGRATH, I. T, JOSHI, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Cell Membrane - analysis Diphenylhexatriene Doxorubicin - therapeutic use E.S.R Electron Spin Resonance Spectroscopy General aspects leukemia P388 Leukemia P388 - analysis Leukemia P388 - drug therapy Leukemia, Experimental - drug therapy lipid structure Medical sciences Membrane Lipids - analysis Mice Microscopy, Fluorescence Pharmacology. Drug treatments plasma membranes
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