Differential role of microtubules in the control of prostaglandin E2 and β-adrenergic stimulation of cyclic AMP accumulation in the rat myometrium

A possible modulatory role of microtubules was investigated for the β-adrenergic and prostaglandin E2 (PGE2)-induced cyclic AMP accumulation in the estrogen-treated rat myometrium. Colchicine, vinblastine and nocodazole, three different antitubulin drugs, enhanced cyclic AMP accumulation caused by P...

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Veröffentlicht in:	Biochemical pharmacology 1983-09, Vol.32 (17), p.2535-2541
Hauptverfasser:	DoKhac, Lien, Tanfin, Zahra, Harbon, Simone
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyl-3-isobutylxanthine - pharmacology Animals Biological and medical sciences Colchicine - pharmacology Cyclic AMP - metabolism Cytochalasin B - pharmacology Dinoprostone Estrogens - pharmacology Female Fundamental and applied biological sciences. Psychology Hormone metabolism and regulation Isoproterenol - pharmacology Kinetics Mammalian female genital system Microtubules - physiology Myometrium - drug effects Myometrium - metabolism Prostaglandins E - pharmacology Rats Uterus - metabolism Vertebrates: reproduction
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