Evidence for the biochemical role of an internal sequence in yeast nuclear mRNA introns: Implications for U1 RNA and metazoan mRNA splicing

Sequence comparison of the introns of two yeast genes (rp51A and rp51B) coding for the same ribosomal protein shows homology only in the last 50 bases of the intron. This region of the intron contains an internal conserved sequence (ICS) present near the 3′ end of all sequenced yeast nuclear mRNA in...

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Veröffentlicht in:Cell 1983, Vol.34 (2), p.395-403
Hauptverfasser: Pikielny, Claudio W., Teem, John L., Rosbash, Michael
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Sprache:eng
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