Fracture healing induces expression of the proto-oncogene c-fos in vivo Possible involvement of the Fos protein in osteoblastic differentiation

Here we report marked in vivo expression of the c-fos gene in the external soft callus (ESC) and periosteal hard callus (PHC) at the fracture site of adult rat tibia. Northern-blot analysis showed that the ESC expressed a high level of c-fos mRNA from post-fracture day 10 to day 28, the time when en...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEBS letters 1991-06, Vol.284 (1), p.42-45
Hauptverfasser:	Ohta, Shuichi, Yamamuro, Takao, Lee, Kaechoong, Okumura, Hideo, Kasai, Ryuichi, Hiraki, Yuji, Ikeda, Toshihiko, Iwasaki, Rempei, Kikuchi, Haruki, Konishi, Junji, Shigeno, Chohei
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline phosphatase Alkaline Phosphatase - genetics Alkaline Phosphatase - metabolism Animals Biological and medical sciences Blotting, Northern c-fos Cell Differentiation - genetics Female Fracture healing Fractures, Bone Fundamental and applied biological sciences. Psychology Gene Expression Immunohistochemistry Molecular and cellular biology Molecular genetics Osteoblastic differentiation Osteoblasts - cytology Osteocalcin - genetics Osteocalcin - metabolism Osteopontin Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins c-fos Proto-Oncogenes Rats Rats, Inbred Strains Sialoglycoproteins - genetics Sialoglycoproteins - metabolism Wound Healing - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!