Inhibition of ornithine decarboxylase in human fibroblast cells by type I and type II interferons

Dilution of human fibroblast GM2767 cell cultures into fresh serum-containing growth medium induces ornithine decarboxylase activity 45-fold over a six-hour interval. When the fibroblast cultures are supplemented with human fibroblast α-, β-, or γ-interferon at the time of dilution into fresh growth...

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Veröffentlicht in:	Biochemical and biophysical research communications 1983-08, Vol.114 (3), p.950-954
Hauptverfasser:	Sekar, Vaithilingam, Atmar, Valerie J., Joshi, Arati R., Krim, Mathilde, Kuehn, Glenn D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Carboxy-Lyases - antagonists & inhibitors Cells, Cultured Enzyme Induction - drug effects Humans Interferon Type I - pharmacology Interferon-gamma - pharmacology Ornithine Decarboxylase Inhibitors
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