Genetic selection for growth rate alters hypothalamic satiety mechanisms in chickens
The relationship between genetic and hypothalamic obesity was investigated by comparing the response to electrolytic lesioning of the ventromedial hypothalamus in chickens from lines developed through divergent selection for high and low body weight. The high-weight line exhibits obesity, while the...
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| Veröffentlicht in: | Behavior genetics 1983-05, Vol.13 (3), p.295-300 |
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| creator | Burkhart, C.A Cherry, J.A Van Krey, H.P Siegel, P.B |
| description | The relationship between genetic and hypothalamic obesity was investigated by comparing the response to electrolytic lesioning of the ventromedial hypothalamus in chickens from lines developed through divergent selection for high and low body weight. The high-weight line exhibits obesity, while the low-weight line is relatively lean. Lesioned adult chickens from the low-weight line exhibited the expected obesity syndrome, while lesioned high-weight-line chickens exhibited neither increased feed consumption nor increased body weight. The results suggested that artificial selection for increased body weight resulted in a diminution of hypothalamic satiety mechanisms. |
| doi_str_mv | 10.1007/bf01071874 |
| format | Article |
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The high-weight line exhibits obesity, while the low-weight line is relatively lean. Lesioned adult chickens from the low-weight line exhibited the expected obesity syndrome, while lesioned high-weight-line chickens exhibited neither increased feed consumption nor increased body weight. The results suggested that artificial selection for increased body weight resulted in a diminution of hypothalamic satiety mechanisms.</description><identifier>ISSN: 0001-8244</identifier><identifier>EISSN: 1573-3297</identifier><identifier>DOI: 10.1007/bf01071874</identifier><identifier>PMID: 6615381</identifier><identifier>CODEN: BHGNAT</identifier><language>eng</language><publisher>New York, NY: Springer</publisher><subject>Animals ; Biological and medical sciences ; Body Weight ; Chickens ; Classical genetics, quantitative genetics, hybrids ; Female ; Fundamental and applied biological sciences. Psychology ; Genetics of eukaryotes. 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The high-weight line exhibits obesity, while the low-weight line is relatively lean. Lesioned adult chickens from the low-weight line exhibited the expected obesity syndrome, while lesioned high-weight-line chickens exhibited neither increased feed consumption nor increased body weight. The results suggested that artificial selection for increased body weight resulted in a diminution of hypothalamic satiety mechanisms.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Body Weight</subject><subject>Chickens</subject><subject>Classical genetics, quantitative genetics, hybrids</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genetics of eukaryotes. Biological and molecular evolution</subject><subject>obesity</subject><subject>Satiation - physiology</subject><subject>Satiety Response - physiology</subject><subject>Selection, Genetic</subject><subject>Ventromedial Hypothalamic Nucleus - physiology</subject><issn>0001-8244</issn><issn>1573-3297</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0U1rHDEMBmBTWpJN2kvvoT6EHArTWv4YzxyT0KSFQA9NzoPGK2fczsfW9hL239dht7nmJIQeBHrF2EcQX0AI-7X3AoSFxuo3bAXGqkrJ1r5lKyEEVI3U-pidpPS7tLLW5ogd1TUY1cCK3d_STDk4nmgkl8Myc79E_hiXpzzwiJk4jpli4sNus-QBR5yeNeZAeccncgPOIU2Jh5m7Ibg_NKf37J3HMdGHQz1lDzff7q-_V3c_b39cX95VTiuZK2jBeimo942kVqOT4LywpvEK0IOvW4VN3_Zro63x5SInhLGoFZFWa23UKbvY793E5e-WUu6mkByNI860bFPXiNpIJfWrEFRdGwBZ4Oc9dHFJKZLvNjFMGHcdiO456-7q5n_WBZ8dtm77idYv9BBumZ8f5pgcjj7i7EJ6YW1dTmpEYZ_2zOPS4WMs5OGXFKDKswRA26p_CyiO8g</recordid><startdate>198305</startdate><enddate>198305</enddate><creator>Burkhart, C.A</creator><creator>Cherry, J.A</creator><creator>Van Krey, H.P</creator><creator>Siegel, P.B</creator><general>Springer</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>198305</creationdate><title>Genetic selection for growth rate alters hypothalamic satiety mechanisms in chickens</title><author>Burkhart, C.A ; Cherry, J.A ; Van Krey, H.P ; Siegel, P.B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c432t-1917f20ebf82e94ac21cf0758f31af1f693a8b9bd5475f297c0057a43ee43d453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Body Weight</topic><topic>Chickens</topic><topic>Classical genetics, quantitative genetics, hybrids</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genetics of eukaryotes. Biological and molecular evolution</topic><topic>obesity</topic><topic>Satiation - physiology</topic><topic>Satiety Response - physiology</topic><topic>Selection, Genetic</topic><topic>Ventromedial Hypothalamic Nucleus - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Burkhart, C.A</creatorcontrib><creatorcontrib>Cherry, J.A</creatorcontrib><creatorcontrib>Van Krey, H.P</creatorcontrib><creatorcontrib>Siegel, P.B</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Behavior genetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Burkhart, C.A</au><au>Cherry, J.A</au><au>Van Krey, H.P</au><au>Siegel, P.B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genetic selection for growth rate alters hypothalamic satiety mechanisms in chickens</atitle><jtitle>Behavior genetics</jtitle><addtitle>Behav Genet</addtitle><date>1983-05</date><risdate>1983</risdate><volume>13</volume><issue>3</issue><spage>295</spage><epage>300</epage><pages>295-300</pages><issn>0001-8244</issn><eissn>1573-3297</eissn><coden>BHGNAT</coden><abstract>The relationship between genetic and hypothalamic obesity was investigated by comparing the response to electrolytic lesioning of the ventromedial hypothalamus in chickens from lines developed through divergent selection for high and low body weight. 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| ispartof | Behavior genetics, 1983-05, Vol.13 (3), p.295-300 |
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| language | eng |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Animals Biological and medical sciences Body Weight Chickens Classical genetics, quantitative genetics, hybrids Female Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution obesity Satiation - physiology Satiety Response - physiology Selection, Genetic Ventromedial Hypothalamic Nucleus - physiology |
| title | Genetic selection for growth rate alters hypothalamic satiety mechanisms in chickens |
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