Regulation of intracellular glutathione levels and lymphocyte functions by lactate

The plasma concentration of lactate varies strongly under physiological and pathological conditions in the range of 1 to 30 m M. High but physiologically relevant lactate concentrations were previously shown to exert strong immunopotentiating effects and to augment the production of interleukin 2 (I...

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Veröffentlicht in:	Cellular immunology 1991-08, Vol.136 (1), p.95-104
Hauptverfasser:	Roth, Steffen, Gmünder, Helmut, Dröge, Wulf
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aspartic Acid - metabolism DNA - biosynthesis Glutathione - analysis Interleukin-2 - metabolism Lactates - pharmacology Lactic Acid Lymphocyte Activation - drug effects Mice Mice, Inbred C3H Mice, Inbred C57BL T-Lymphocytes - drug effects T-Lymphocytes - immunology T-Lymphocytes, Cytotoxic - drug effects T-Lymphocytes, Cytotoxic - immunology Uridine - metabolism
Online-Zugang:	Volltext
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