Evaluation of a New Bipyridine Inotropic Agent — Milrinone — in Patients with Severe Congestive Heart Failure

Milrinone, a derivative of amrinone, has nearly 20 times the inotropic potency of the parent compound and does not cause fever or thrombocytopenia in normal volunteers or in animals sensitive to amrinone. In 20 patients with severe congestive heart failure, intravenous milrinone resulted in signific...

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Veröffentlicht in:	The New England journal of medicine 1983-09, Vol.309 (13), p.748-756
Hauptverfasser:	Baim, Donald S, McDowell, Arthur V, Cherniles, Joseph, Monrad, Ernest S, Parker, J. Anthony, Edelson, Jerome, Braunwald, Eugene, Grossman, William
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Aged Angina Blood pressure Cardiomyopathy Cardiotonic Agents - administration & dosage Cardiotonic Agents - pharmacology Cardiotonic Agents - therapeutic use Cardiovascular disease Catheters Congestive heart failure Coronary artery Drug Evaluation Drug therapy Female Fever Follow-Up Studies Heart failure Heart Failure - diagnostic imaging Heart Failure - drug therapy Heart rate Heart Ventricles - diagnostic imaging Hemodynamics - drug effects Hospitals Humans Injections, Intravenous Intolerance Intravenous administration Intubation Laboratory animals Male Middle Aged Milrinone Patients Pyridones - administration & dosage Pyridones - pharmacology Pyridones - therapeutic use Radionuclide Imaging Research centers Short term Smooth muscle Thrombocytopenia Ventricle
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