Dose-response effects of oral yohimbine in unrestrained primates

Six unrestrained bonnet macaques were each observed after oral administration of four dosages of yohimbine hydrochloride (0.10, 0.25, 0.50, and 0.75 mg/kg) and a placebo. Yohimbine significantly increased episodes of motoric activation and affective response interspersed with intervals of behavioral...

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Veröffentlicht in:	Biological psychiatry (1969) 1991-04, Vol.29 (7), p.647-657
Hauptverfasser:	Rosenblum, Leonard A., Coplan, Jeremy D., Friedman, Steven, Bassoff, Trina
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Arousal - drug effects Behavior, Animal - drug effects Biological and medical sciences Catecholaminergic system Dose-Response Relationship, Drug Locus Coeruleus - drug effects Macaca radiata Male Medical sciences Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Panic - drug effects Pharmacology. Drug treatments Receptors, Adrenergic - drug effects Social Environment Yohimbine - pharmacology
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