Enhancement of Chemotactic Migration by the Local Anesthetic Tetracaine

The local amine anesthetic tetracaine added to a suspension of guinea pig or human neutrophilic granulocytes inhibited their random migration in Boyden chambers, but increased their chemotactic migration towards the chemotactic tripeptide f-Met-Leu-Phe, complement-activated normal guinea pig serum,...

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Veröffentlicht in:	Immunobiology (1979) 1983-07, Vol.165 (1), p.97-106
Hauptverfasser:	Kownatzki, E., Uhrich, Sibylle
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Physiological Phenomena Buffers Cell Movement - drug effects Chemotactic Factors, Eosinophil - physiology Chemotaxis, Leukocyte - drug effects Guinea Pigs Humans N-Formylmethionine - analogs & derivatives N-Formylmethionine - pharmacology N-Formylmethionine Leucyl-Phenylalanine Neutrophils Oligopeptides - pharmacology Serum Albumin, Bovine - pharmacology Tetracaine - pharmacology
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