Inhibition of gastric acid secretion by omeprazole in the dog and rat

The gastric antisecretory properties of omeprazole, a new potent substituted benzimidazole, have been evaluated in dogs and rats. Omeprazole was compared with another benzimidazole, picoprazole (H 149/94), and with the histamine H2-receptor antagonist cimetidine. The intravenous or intraduodenal adm...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 1983-10, Vol.85 (4), p.900-907
Hauptverfasser:	Larsson, Håkan, Carlsson, Enar, Junggren, Ulf, Olbe, Lars, Sjöstrand, Sven Erik, Skånberg, Inger, Sundell, Gunhild
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Pyridinylmethylsulfinylbenzimidazoles Administration, Oral Animals Benzimidazoles - administration & dosage Benzimidazoles - blood Benzimidazoles - pharmacology Biological and medical sciences Cimetidine Digestive system Dogs Duodenum Female Gastric Acid - secretion Injections, Intravenous Male Medical sciences Omeprazole Pharmacology. Drug treatments Rats Rats, Inbred Strains Vagotomy
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