Identification of Pro-Opiomelanocortin-Derived Peptides in the Human Adrenal Medulla

Extracts from adult human adrenals contained high concentrations of immunoreactive β-endorphin and α-melanotropin. Lower quantities of immunoreactive adrenocorticotropic hormone could also be detected. Distribution studies showed the presence of pro-opiomelanocortin fragments in the adrenal medulla....

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1983-09, Vol.221 (4614), p.957-960
Hauptverfasser:	Evans, Christopher J., Erdelyi, Elizabeth, Weber, Eckard, Barchas, Jack D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal cortex Adrenal Cortex - analysis Adrenal glands Adrenal medulla Adrenal Medulla - analysis Adrenocorticotropic Hormone - analysis Analytical, structural and metabolic biochemistry Antibodies Biological and medical sciences Endorphins Endorphins - analysis Fundamental and applied biological sciences. Psychology Gels Glycoproteins Hormones Humans Materials Melanocyte-Stimulating Hormones - analysis Neurochemistry Opioid peptides Pituitary Hormones, Anterior - analysis Pituitary Hormones, Anterior - metabolism Pro-Opiomelanocortin Protein Precursors - analysis Protein Precursors - metabolism Proteins Radioimmunoassay
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