Human Papilloma Virus in Multifocal, Invasive Female Genital Tract Malignancy

Two young patients with multifocal, invasive, verrucoid carcinomas of the lower genital tract are described. Viral particles consistent with human papilloma virus were demonstrated by transmission electron microscopy in areas of koilocytotic malignant and nonmalignant epithelium, and both patients h...

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Veröffentlicht in:	Obstetrics and gynecology (New York. 1953) 1983-09, Vol.62 (3 Suppl), p.83S-87S
Hauptverfasser:	WEED, JOHN C, LOZIER, CYNTHIA, DANIEL, SARA JO
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Carcinoma, Squamous Cell - diagnosis Condylomata Acuminata - diagnosis Condylomata Acuminata - microbiology Female Female genital diseases Genital Neoplasms, Female - diagnosis Genital Neoplasms, Female - microbiology Gynecology. Andrology. Obstetrics Humans Medical sciences Neoplasms, Multiple Primary - diagnosis Papillomaviridae - isolation & purification Tumors
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Beschreibung
Zusammenfassung:	Two young patients with multifocal, invasive, verrucoid carcinomas of the lower genital tract are described. Viral particles consistent with human papilloma virus were demonstrated by transmission electron microscopy in areas of koilocytotic malignant and nonmalignant epithelium, and both patients had evidence of impaired immune function. The role of human papilloma virus in genital neoplasia is discussed.
ISSN:	0029-7844 1873-233X