MILBEMYCINS, A NEW FAMILY OF MACROLIDE ANTIBIOTICS: FERMENTATION, ISOLATION, PHYSICO-CHEMICAL PROPERTIES AND BIOCONVERSION OF MILBEMYCINS J AND K

Strain Rf-107, a mutant of Streptomyces hygroscopicus subsp. aureolacrimosus, obtained with ultraviolet irradiation, produced two new macrolide antibiotics, milbemycins J and K without production of any of the other milbemycins described in the previous paper. Fermentation studies on the strain were...

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Veröffentlicht in:	Journal of antibiotics 1983, Vol.36(5), pp.509-515
Hauptverfasser:	ONO, MICHIHISA, MISHIMA, HIROSHI, TAKIGUCHI, YO, TERAO, MICHIYA
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents Chemical Phenomena Chemistry Fermentation Lactones - biosynthesis Lactones - isolation & purification Macrolides Streptomyces - metabolism Streptomyces hygroscopicus
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