THE PREPARATION AND DETERMINATION OF STRUCTURE OF BENZYLPENICILLOYL COMPOUNDS USED IN SKIN-TESTING FOR PENICILLIN ALLERGY

THE PREPARATION AND DETERMINATION OF STRUCTURE OF BENZYLPENICILLOYL COMPOUNDS USED IN SKIN-TESTING FOR PENICILLIN ALLERGY

The preparation of α-D-benzylpenicilloyl-n-propylamine and octa-ε-(α-D-benzylpenicilloyl)-octa-α-L-lysine are described. Their structures were established by chemical and spectroscopic evidence. Proton and carbon-13 nuclear magnetic resonance spectra of these two penicillin derivatives and some rela...

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Veröffentlicht in:Journal of antibiotics 1983, Vol.36(6), pp.709-714
Hauptverfasser: GOLDSCHMIDT, BERNARD M., LEVINE, BERNARD B.
Format: Artikel
Sprache:eng
Schlagworte:
Humans
Hypersensitivity
Magnetic Resonance Spectroscopy
Penicillin G - analogs & derivatives
Penicillin G - chemical synthesis
Penicillin G - immunology
Skin Tests
Structure-Activity Relationship
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container_end_page 714
container_issue 6
container_start_page 709
container_title Journal of antibiotics
container_volume 36
creator GOLDSCHMIDT, BERNARD M.
LEVINE, BERNARD B.
description The preparation of α-D-benzylpenicilloyl-n-propylamine and octa-ε-(α-D-benzylpenicilloyl)-octa-α-L-lysine are described. Their structures were established by chemical and spectroscopic evidence. Proton and carbon-13 nuclear magnetic resonance spectra of these two penicillin derivatives and some related compounds are provided. These compounds are useful in skin testing for penicillin allergy.
doi_str_mv 10.7164/antibiotics.36.709
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Antibiot.</addtitle><description>The preparation of α-D-benzylpenicilloyl-n-propylamine and octa-ε-(α-D-benzylpenicilloyl)-octa-α-L-lysine are described. Their structures were established by chemical and spectroscopic evidence. Proton and carbon-13 nuclear magnetic resonance spectra of these two penicillin derivatives and some related compounds are provided. 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subjects Humans
Hypersensitivity
Magnetic Resonance Spectroscopy
Penicillin G - analogs & derivatives
Penicillin G - chemical synthesis
Penicillin G - immunology
Skin Tests
Structure-Activity Relationship
title THE PREPARATION AND DETERMINATION OF STRUCTURE OF BENZYLPENICILLOYL COMPOUNDS USED IN SKIN-TESTING FOR PENICILLIN ALLERGY
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