Species specificity of immunity to malignant transformed cultured insect cells
The specificity of malignantly transformed cultured cells of the German cockroach was assayed by injecting the cells into eight additional species of cockroaches in three families. All species but the most advanced one were susceptible. The range of lethal times for the different species reflected t...
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Veröffentlicht in: | Developmental and comparative immunology 1983-01, Vol.7 (2), p.241-252 |
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description | The specificity of malignantly transformed cultured cells of the German cockroach was assayed by injecting the cells into eight additional species of cockroaches in three families. All species but the most advanced one were susceptible. The range of lethal times for the different species reflected their relationship to the species from which the cells originated. The abilities of the injected hosts to encapsulate implants of embryo fragments of the German cockroach and microcarrier beads paralleled their resistance against the malignant cells. The order of susceptibility of the cockroach species to a pathogenic amoeba paralleled their susceptibility to the malignant cells, but death from the amoeba occurred in a much shorter time. Hematocrit values were higher in the more resistant species. |
doi_str_mv | 10.1016/0145-305X(83)90005-8 |
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All species but the most advanced one were susceptible. The range of lethal times for the different species reflected their relationship to the species from which the cells originated. The abilities of the injected hosts to encapsulate implants of embryo fragments of the German cockroach and microcarrier beads paralleled their resistance against the malignant cells. The order of susceptibility of the cockroach species to a pathogenic amoeba paralleled their susceptibility to the malignant cells, but death from the amoeba occurred in a much shorter time. 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Hematocrit values were higher in the more resistant species.</description><subject>Amebiasis - immunology</subject><subject>Amebiasis - veterinary</subject><subject>Animals</subject><subject>Blattella germanica</subject><subject>Blattellidae</subject><subject>Cell Line</subject><subject>Cell Transformation, Neoplastic - pathology</subject><subject>Cockroaches - immunology</subject><subject>Cockroaches - parasitology</subject><subject>Hematocrit</subject><subject>Species Specificity</subject><issn>0145-305X</issn><issn>1879-0089</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLxDAQgIMouj7-gUJPoofqJGna9CKI-IJFDyp4C2k6kUgfa9IK--9N3WWPepqB-eb1EXJM4YICzS-BZiLlIN7PJD8vAUCkcovMqCzKFECW22S2QfbIfgifkQFJYZfs5rLgGeMz8vSyQOMwJGGK1hk3LJPeJq5tx27Khz5pdeM-Ot0NyeB1F2zvW6wTMzbD6GPiuoBmSAw2TTgkO1Y3AY_W8YC83d2-3jyk8-f7x5vreWo4L4aU51QwDcBKVhhAZoWpBKu4ZLausoKVWNlacFkjYoHWVJIzq01Nc1lrbYAfkNPV3IXvv0YMg2pdmC7QHfZjUBJEQWX88D-Q8jwTPJcRzFag8X0IHq1aeNdqv1QU1ORbTTLVJFNJrn59q6ntZD1_rKKVTdNacKxfreoYbXw79CpE3Z3B2vloTdW9-3vBDx9pkQY</recordid><startdate>19830101</startdate><enddate>19830101</enddate><creator>Tsang, K.Roger</creator><creator>Brooks, Marion A.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19830101</creationdate><title>Species specificity of immunity to malignant transformed cultured insect cells</title><author>Tsang, K.Roger ; Brooks, Marion A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c337t-36152a002927c0e2f5cb52b382fdb4729ebfd538deee7efcb832facd168daac03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Amebiasis - immunology</topic><topic>Amebiasis - veterinary</topic><topic>Animals</topic><topic>Blattella germanica</topic><topic>Blattellidae</topic><topic>Cell Line</topic><topic>Cell Transformation, Neoplastic - pathology</topic><topic>Cockroaches - immunology</topic><topic>Cockroaches - parasitology</topic><topic>Hematocrit</topic><topic>Species Specificity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tsang, K.Roger</creatorcontrib><creatorcontrib>Brooks, Marion A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Developmental and comparative immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tsang, K.Roger</au><au>Brooks, Marion A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Species specificity of immunity to malignant transformed cultured insect cells</atitle><jtitle>Developmental and comparative immunology</jtitle><addtitle>Dev Comp Immunol</addtitle><date>1983-01-01</date><risdate>1983</risdate><volume>7</volume><issue>2</issue><spage>241</spage><epage>252</epage><pages>241-252</pages><issn>0145-305X</issn><eissn>1879-0089</eissn><abstract>The specificity of malignantly transformed cultured cells of the German cockroach was assayed by injecting the cells into eight additional species of cockroaches in three families. 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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Amebiasis - immunology Amebiasis - veterinary Animals Blattella germanica Blattellidae Cell Line Cell Transformation, Neoplastic - pathology Cockroaches - immunology Cockroaches - parasitology Hematocrit Species Specificity |
title | Species specificity of immunity to malignant transformed cultured insect cells |
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