Incidence and specificity of antibodies to types I, II, III, IV, and V collagen in rheumatoid arthritis and other rheumatic diseases as measured by 125i‐radioimmunoassay

Antibodies to human native and denatured types I, II, III, IV, and V collagens were measured using 125I‐radioimmunoassay. Mean levels of binding by sera from 30 rheumatoid arthritis patients were significantly higher than those from 20 normal subjects against all of the collagens tested. The relativ...

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