Differentiation of aggregated murine P19 embryonal carcinoma cells is induced by a novel visceral endoderm-specific FGF-like factor and inhibited by activin A

Aggregation of P19 embryonal carcinoma cells in the presence of a factor, secreted by the visceral endoderm-like cell line END-2, induces differentiation to cell types including visceral endoderm, mesoderm-derived muscle tissue and neurons. This factor is different from activin A, type β transformin...

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Veröffentlicht in:	Mechanisms of development 1991-02, Vol.33 (2), p.157-165
Hauptverfasser:	van den Eijnden-van Raaij, A.J.M., van Achterberg, T.A.E., van der Kruijssen, C.M.M., Piersma, A.H., Huylebroeck, D., de Laat, S.W., Mummery, C.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Activin A Activins Aggregation Animals Cell Differentiation - physiology Cell Line Embryonal carcinoma cells Embryonal Carcinoma Stem Cells Endoderm - metabolism Fibroblast Growth Factors - metabolism Fibroblast Growth Factors - physiology Growth factor Inhibins - physiology Mesoderm Mice Neoplastic Stem Cells - cytology Viscera - cytology Viscera - embryology Viscera - metabolism Visceral endoderm
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