Androgen metabolism by hepatic and renal tissues of the fetal rhesus monkey

Liver and kidney from fetal monkeys (day 125 of gestation) were fractionated into low speed pellets, microsomal and cytosolic fractions. Liver cytosols converted as much testosterone (T) to 5β-androstane-3α,17β-diol (5β-diol) at 0°C as at 4°–45°C without exogenous cofactors. The principal product fo...

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