Chorionic villus sampling for fetal karyotyping in missed abortions
Chorionic villus sampling (CVS) was performed in 12 pregnant women (9–25 gestational weeks) with ultrasonographic evidence of missed abortion. An ultrasonographically guided transabdominal (eight cases) or transcervical (four cases) approach was used. Fetal karyo‐typing was successful in all cases;...
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| Veröffentlicht in: | Prenatal diagnosis 1991-01, Vol.11 (1), p.55-57 |
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| container_title | Prenatal diagnosis |
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| creator | Appleman, Z. Rosensaft, J. Elchalal, U. Caspi, B. Chemke, J. |
| description | Chorionic villus sampling (CVS) was performed in 12 pregnant women (9–25 gestational weeks) with ultrasonographic evidence of missed abortion. An ultrasonographically guided transabdominal (eight cases) or transcervical (four cases) approach was used. Fetal karyo‐typing was successful in all cases; in five, chromosomal aberrations were found and in seven, chromosome analyses revealed normal karyotypes. Tissue culture for fetal karyotyping was successful in only 72.5 per cent of 40 live pregnancies which were electively interrupted because of abnormal ultrasonographic findings or an abnormal fetal karyotype, and in 57 per cent of seven missed abortions. CVS is suggested as a feasible and effective method for fetal karyotyping in missed abortions and it seems to be superior to post‐abortion tissue culture. |
| doi_str_mv | 10.1002/pd.1970110110 |
| format | Article |
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An ultrasonographically guided transabdominal (eight cases) or transcervical (four cases) approach was used. Fetal karyo‐typing was successful in all cases; in five, chromosomal aberrations were found and in seven, chromosome analyses revealed normal karyotypes. Tissue culture for fetal karyotyping was successful in only 72.5 per cent of 40 live pregnancies which were electively interrupted because of abnormal ultrasonographic findings or an abnormal fetal karyotype, and in 57 per cent of seven missed abortions. CVS is suggested as a feasible and effective method for fetal karyotyping in missed abortions and it seems to be superior to post‐abortion tissue culture.</description><identifier>ISSN: 0197-3851</identifier><identifier>EISSN: 1097-0223</identifier><identifier>DOI: 10.1002/pd.1970110110</identifier><identifier>PMID: 2027855</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>abortion ; Abortion, Missed - diagnostic imaging ; Abortion, Missed - genetics ; Chorionic Villi Sampling ; Chorionic villus sampling ; Chromosome Aberrations ; Culture Techniques ; Female ; Humans ; Karyotype ; Karyotyping ; Missed abortion ; Pregnancy ; Ultrasonography</subject><ispartof>Prenatal diagnosis, 1991-01, Vol.11 (1), p.55-57</ispartof><rights>Copyright © 1991 John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4050-213510bd2ad7fde9ea1422a434c8208765684d56f436b626ab3e55565a95ce3d3</citedby><cites>FETCH-LOGICAL-c4050-213510bd2ad7fde9ea1422a434c8208765684d56f436b626ab3e55565a95ce3d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fpd.1970110110$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fpd.1970110110$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,778,782,1414,27907,27908,45557,45558</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2027855$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Appleman, Z.</creatorcontrib><creatorcontrib>Rosensaft, J.</creatorcontrib><creatorcontrib>Elchalal, U.</creatorcontrib><creatorcontrib>Caspi, B.</creatorcontrib><creatorcontrib>Chemke, J.</creatorcontrib><title>Chorionic villus sampling for fetal karyotyping in missed abortions</title><title>Prenatal diagnosis</title><addtitle>Prenat. Diagn</addtitle><description>Chorionic villus sampling (CVS) was performed in 12 pregnant women (9–25 gestational weeks) with ultrasonographic evidence of missed abortion. An ultrasonographically guided transabdominal (eight cases) or transcervical (four cases) approach was used. Fetal karyo‐typing was successful in all cases; in five, chromosomal aberrations were found and in seven, chromosome analyses revealed normal karyotypes. Tissue culture for fetal karyotyping was successful in only 72.5 per cent of 40 live pregnancies which were electively interrupted because of abnormal ultrasonographic findings or an abnormal fetal karyotype, and in 57 per cent of seven missed abortions. CVS is suggested as a feasible and effective method for fetal karyotyping in missed abortions and it seems to be superior to post‐abortion tissue culture.</description><subject>abortion</subject><subject>Abortion, Missed - diagnostic imaging</subject><subject>Abortion, Missed - genetics</subject><subject>Chorionic Villi Sampling</subject><subject>Chorionic villus sampling</subject><subject>Chromosome Aberrations</subject><subject>Culture Techniques</subject><subject>Female</subject><subject>Humans</subject><subject>Karyotype</subject><subject>Karyotyping</subject><subject>Missed abortion</subject><subject>Pregnancy</subject><subject>Ultrasonography</subject><issn>0197-3851</issn><issn>1097-0223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1LAzEQxYMotVaPHoU9edua72SPUrUKpRap6C1kN1mN3S-Trdr_3i0tFS8KAwPzfvOYeQCcIjhEEOKLxgxRIiBC69oDfQQTEUOMyT7ow06JiWToEByF8NbhEieiB3oYYiEZ64PR6LX2rq5cFn24oliGKOiyKVz1EuW1j3Lb6iJaaL-q21WznroqKl0I1kQ6rX3brYZjcJDrItiTbR-Ax5vr-eg2ntyP70aXkzijkMEYI8IQTA3WRuTGJlYjirGmhGYSQyk445IaxnNKeMox1ymxjDHOdMIySwwZgPONb-Pr96UNreouyWxR6MrWy6AkZDSRMPkXRExSSSnpwHgDZr4OwdtcNd6V3bcKQbVOVzVG_aTb8Wdb42VaWrOjt3F2utjon66wq7_N1Ozql_P2Ehda-7Xb1H6huCCCqafpWIk5n-LZw0Q9k28gcJMU</recordid><startdate>199101</startdate><enddate>199101</enddate><creator>Appleman, Z.</creator><creator>Rosensaft, J.</creator><creator>Elchalal, U.</creator><creator>Caspi, B.</creator><creator>Chemke, J.</creator><general>John Wiley & Sons, Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T3</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>199101</creationdate><title>Chorionic villus sampling for fetal karyotyping in missed abortions</title><author>Appleman, Z. ; Rosensaft, J. ; Elchalal, U. ; Caspi, B. ; Chemke, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4050-213510bd2ad7fde9ea1422a434c8208765684d56f436b626ab3e55565a95ce3d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>abortion</topic><topic>Abortion, Missed - diagnostic imaging</topic><topic>Abortion, Missed - genetics</topic><topic>Chorionic Villi Sampling</topic><topic>Chorionic villus sampling</topic><topic>Chromosome Aberrations</topic><topic>Culture Techniques</topic><topic>Female</topic><topic>Humans</topic><topic>Karyotype</topic><topic>Karyotyping</topic><topic>Missed abortion</topic><topic>Pregnancy</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Appleman, Z.</creatorcontrib><creatorcontrib>Rosensaft, J.</creatorcontrib><creatorcontrib>Elchalal, U.</creatorcontrib><creatorcontrib>Caspi, B.</creatorcontrib><creatorcontrib>Chemke, J.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Human Genome Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Prenatal diagnosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Appleman, Z.</au><au>Rosensaft, J.</au><au>Elchalal, U.</au><au>Caspi, B.</au><au>Chemke, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chorionic villus sampling for fetal karyotyping in missed abortions</atitle><jtitle>Prenatal diagnosis</jtitle><addtitle>Prenat. Diagn</addtitle><date>1991-01</date><risdate>1991</risdate><volume>11</volume><issue>1</issue><spage>55</spage><epage>57</epage><pages>55-57</pages><issn>0197-3851</issn><eissn>1097-0223</eissn><abstract>Chorionic villus sampling (CVS) was performed in 12 pregnant women (9–25 gestational weeks) with ultrasonographic evidence of missed abortion. An ultrasonographically guided transabdominal (eight cases) or transcervical (four cases) approach was used. Fetal karyo‐typing was successful in all cases; in five, chromosomal aberrations were found and in seven, chromosome analyses revealed normal karyotypes. Tissue culture for fetal karyotyping was successful in only 72.5 per cent of 40 live pregnancies which were electively interrupted because of abnormal ultrasonographic findings or an abnormal fetal karyotype, and in 57 per cent of seven missed abortions. CVS is suggested as a feasible and effective method for fetal karyotyping in missed abortions and it seems to be superior to post‐abortion tissue culture.</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>2027855</pmid><doi>10.1002/pd.1970110110</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0197-3851 |
| ispartof | Prenatal diagnosis, 1991-01, Vol.11 (1), p.55-57 |
| issn | 0197-3851 1097-0223 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | abortion Abortion, Missed - diagnostic imaging Abortion, Missed - genetics Chorionic Villi Sampling Chorionic villus sampling Chromosome Aberrations Culture Techniques Female Humans Karyotype Karyotyping Missed abortion Pregnancy Ultrasonography |
| title | Chorionic villus sampling for fetal karyotyping in missed abortions |
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