Heparin and a low molecular weight fraction enhances thrombolysis and by this pathway exercises a protective effect against thrombosis

In human volunteers unfractionated heparin and a low molecular weight fraction of heparin (LMWH) caused an increase in plasma plasminogen activator (PA) which peaked at 3 hours after subcutaneous injection. Using a perfused isolated rabbit ear model the enhancement of PA activity was confirmed and w...

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Veröffentlicht in:	Thrombosis research 1983-05, Vol.30 (3), p.219-224
Hauptverfasser:	Vairel, E.G., Bouty-Boye, H., Toulemonde, F., Doutremepuich, C., Marsh, N.A., Gaffney, P.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Fibrinolytic Agents - pharmacology Heparin Heparin - pharmacology Heparin fractions Humans Male Molecular Weight Plasminogen activator Plasminogen Activators - analysis Rabbits Thrombolysis Thrombosis - prevention & control
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