Secretion of sphingolipid hydrolase activator precursor, prosaposin

Sphingolipid hydrolases are activated by activator proteins or saposins. The precursor protein has been expected from the studies on the cDNA for saposins. Here we demonstrate that prosaposin occurs in various kinds of human secretory fluids such as cerebrospinal fluid, semen, milk, pancreatic juice...

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Veröffentlicht in:	Biochemical and biophysical research communications 1991-04, Vol.176 (2), p.668-674
Hauptverfasser:	Hineno, Takashi, Sano, Akira, Kondoh, Keiji, Ueno, Shu-ichi, Kakimoto, Yasuo, Yoshida, Ken-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - pharmacology Adult Biological and medical sciences Blood Platelets - drug effects Blood Platelets - enzymology Blood Platelets - metabolism Cell physiology Collagen - pharmacology DNA - metabolism Enzyme Activation - drug effects Epinephrine - pharmacology Fundamental and applied biological sciences. Psychology Glycoproteins - genetics Glycoproteins - metabolism Humans Hydrolases - metabolism Lactation Male Milk, Human - enzymology Molecular and cellular biology Organ Specificity Protein Precursors - metabolism Saposins Secretion. Exocytosis Sphingolipids - metabolism
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