Multicenter Trial of Collagraft as Bone Graft Substitute
Collagraft (Zimmer and Collagen Corporation) consists of a mixture of porous beads composed of 60% hydroxyapatite and 40% tricalcium phosphate ceramic and fibrillar collagen. When mixed with autogenous bone marrow, it serves as an effective bone graft substitute. Since September 1986, this material...
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| Veröffentlicht in: | Journal of orthopaedic trauma 1991, Vol.5 (1), p.1-8 |
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| container_title | Journal of orthopaedic trauma |
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| creator | CORNELL, C. N LANE, J. M MERKOW, R SELIGSON, D HENRY, S GUSTILO, R VINCENT, K CHAPMAN, M |
| description | Collagraft (Zimmer and Collagen Corporation) consists of a mixture of porous beads composed of 60% hydroxyapatite and 40% tricalcium phosphate ceramic and fibrillar collagen. When mixed with autogenous bone marrow, it serves as an effective bone graft substitute. Since September 1986, this material has been used in a multiclinic prospective trial, randomized against cancellous iliac crest autografts in the treatment of long bone fractures. To date, 267 patients have entered this study with 128 patients receiving cancellous autograft and 139 patients receiving Collagraft. At 6− and 12-month follow-ups, Collagraft appears to function as well as autogenous graft when used in the treatment of acute long bone fractures. |
| doi_str_mv | 10.1097/00005131-199103000-00001 |
| format | Article |
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N ; LANE, J. M ; MERKOW, R ; SELIGSON, D ; HENRY, S ; GUSTILO, R ; VINCENT, K ; CHAPMAN, M</creator><creatorcontrib>CORNELL, C. N ; LANE, J. M ; MERKOW, R ; SELIGSON, D ; HENRY, S ; GUSTILO, R ; VINCENT, K ; CHAPMAN, M</creatorcontrib><description>Collagraft (Zimmer and Collagen Corporation) consists of a mixture of porous beads composed of 60% hydroxyapatite and 40% tricalcium phosphate ceramic and fibrillar collagen. When mixed with autogenous bone marrow, it serves as an effective bone graft substitute. Since September 1986, this material has been used in a multiclinic prospective trial, randomized against cancellous iliac crest autografts in the treatment of long bone fractures. To date, 267 patients have entered this study with 128 patients receiving cancellous autograft and 139 patients receiving Collagraft. At 6− and 12-month follow-ups, Collagraft appears to function as well as autogenous graft when used in the treatment of acute long bone fractures.</description><identifier>ISSN: 0890-5339</identifier><identifier>EISSN: 1531-2291</identifier><identifier>DOI: 10.1097/00005131-199103000-00001</identifier><identifier>PMID: 2023034</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott-Raven Publishers</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Bone Transplantation ; Calcium Phosphates ; Collagen ; Follow-Up Studies ; Fracture Fixation ; Fractures, Bone - physiopathology ; Fractures, Bone - surgery ; Humans ; Injuries of the limb. Injuries of the spine ; Male ; Medical sciences ; Middle Aged ; Prospective Studies ; Prostheses and Implants ; Traumas. Diseases due to physical agents ; Wound Healing</subject><ispartof>Journal of orthopaedic trauma, 1991, Vol.5 (1), p.1-8</ispartof><rights>Lippincott-Raven Publishers.</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4361-b237fac9a2e04c62d606b4d8bebbfa35380b29bea519b3a149272e021a3d4bf3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4023,27922,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19603410$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2023034$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CORNELL, C. N</creatorcontrib><creatorcontrib>LANE, J. M</creatorcontrib><creatorcontrib>MERKOW, R</creatorcontrib><creatorcontrib>SELIGSON, D</creatorcontrib><creatorcontrib>HENRY, S</creatorcontrib><creatorcontrib>GUSTILO, R</creatorcontrib><creatorcontrib>VINCENT, K</creatorcontrib><creatorcontrib>CHAPMAN, M</creatorcontrib><title>Multicenter Trial of Collagraft as Bone Graft Substitute</title><title>Journal of orthopaedic trauma</title><addtitle>J Orthop Trauma</addtitle><description>Collagraft (Zimmer and Collagen Corporation) consists of a mixture of porous beads composed of 60% hydroxyapatite and 40% tricalcium phosphate ceramic and fibrillar collagen. When mixed with autogenous bone marrow, it serves as an effective bone graft substitute. Since September 1986, this material has been used in a multiclinic prospective trial, randomized against cancellous iliac crest autografts in the treatment of long bone fractures. To date, 267 patients have entered this study with 128 patients receiving cancellous autograft and 139 patients receiving Collagraft. At 6− and 12-month follow-ups, Collagraft appears to function as well as autogenous graft when used in the treatment of acute long bone fractures.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Bone Transplantation</subject><subject>Calcium Phosphates</subject><subject>Collagen</subject><subject>Follow-Up Studies</subject><subject>Fracture Fixation</subject><subject>Fractures, Bone - physiopathology</subject><subject>Fractures, Bone - surgery</subject><subject>Humans</subject><subject>Injuries of the limb. Injuries of the spine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Prostheses and Implants</subject><subject>Traumas. Diseases due to physical agents</subject><subject>Wound Healing</subject><issn>0890-5339</issn><issn>1531-2291</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kctOwzAQRS0EKqXwCUjZwC7gVx5eQgUFqYgF3Vtjx6EBNym2o4q_x21DWeGNNXfO3LGuEUoIviFYFLc4nowwkhIhCGaxSrcSOUJjkkWZUkGO0RiXAqcZY-IUnXn_EYkSUzpCI4opw4yPUfnS29Bo0wbjkoVrwCZdnUw7a-HdQR0S8Ml915pktqveeuVDE_pgztFJDdabi-GeoMXjw2L6lM5fZ8_Tu3mqOctJqigratACqMFc57TKca54VSqjVA0sYyVWVCgDGRGKAeGCFhGlBFjFVc0m6Hpvu3bdV298kKvGaxOf15qu97LEW4uCR7Dcg9p13jtTy7VrVuC-JcFym5n8zUweMttJJI5eDjt6tTLVYXAIKfavhj54DbZ20OrG__mLPFLRcYL4ntt0NsbpP22_MU4uDdiwlP99GfsB0eWCCQ</recordid><startdate>1991</startdate><enddate>1991</enddate><creator>CORNELL, C. N</creator><creator>LANE, J. M</creator><creator>MERKOW, R</creator><creator>SELIGSON, D</creator><creator>HENRY, S</creator><creator>GUSTILO, R</creator><creator>VINCENT, K</creator><creator>CHAPMAN, M</creator><general>Lippincott-Raven Publishers</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1991</creationdate><title>Multicenter Trial of Collagraft as Bone Graft Substitute</title><author>CORNELL, C. N ; LANE, J. M ; MERKOW, R ; SELIGSON, D ; HENRY, S ; GUSTILO, R ; VINCENT, K ; CHAPMAN, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4361-b237fac9a2e04c62d606b4d8bebbfa35380b29bea519b3a149272e021a3d4bf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Bone Transplantation</topic><topic>Calcium Phosphates</topic><topic>Collagen</topic><topic>Follow-Up Studies</topic><topic>Fracture Fixation</topic><topic>Fractures, Bone - physiopathology</topic><topic>Fractures, Bone - surgery</topic><topic>Humans</topic><topic>Injuries of the limb. Injuries of the spine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Prostheses and Implants</topic><topic>Traumas. Diseases due to physical agents</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CORNELL, C. N</creatorcontrib><creatorcontrib>LANE, J. M</creatorcontrib><creatorcontrib>MERKOW, R</creatorcontrib><creatorcontrib>SELIGSON, D</creatorcontrib><creatorcontrib>HENRY, S</creatorcontrib><creatorcontrib>GUSTILO, R</creatorcontrib><creatorcontrib>VINCENT, K</creatorcontrib><creatorcontrib>CHAPMAN, M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of orthopaedic trauma</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>CORNELL, C. N</au><au>LANE, J. M</au><au>MERKOW, R</au><au>SELIGSON, D</au><au>HENRY, S</au><au>GUSTILO, R</au><au>VINCENT, K</au><au>CHAPMAN, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multicenter Trial of Collagraft as Bone Graft Substitute</atitle><jtitle>Journal of orthopaedic trauma</jtitle><addtitle>J Orthop Trauma</addtitle><date>1991</date><risdate>1991</risdate><volume>5</volume><issue>1</issue><spage>1</spage><epage>8</epage><pages>1-8</pages><issn>0890-5339</issn><eissn>1531-2291</eissn><abstract>Collagraft (Zimmer and Collagen Corporation) consists of a mixture of porous beads composed of 60% hydroxyapatite and 40% tricalcium phosphate ceramic and fibrillar collagen. When mixed with autogenous bone marrow, it serves as an effective bone graft substitute. Since September 1986, this material has been used in a multiclinic prospective trial, randomized against cancellous iliac crest autografts in the treatment of long bone fractures. To date, 267 patients have entered this study with 128 patients receiving cancellous autograft and 139 patients receiving Collagraft. At 6− and 12-month follow-ups, Collagraft appears to function as well as autogenous graft when used in the treatment of acute long bone fractures.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott-Raven Publishers</pub><pmid>2023034</pmid><doi>10.1097/00005131-199103000-00001</doi><tpages>8</tpages></addata></record> |
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| identifier | ISSN: 0890-5339 |
| ispartof | Journal of orthopaedic trauma, 1991, Vol.5 (1), p.1-8 |
| issn | 0890-5339 1531-2291 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent Adult Biological and medical sciences Bone Transplantation Calcium Phosphates Collagen Follow-Up Studies Fracture Fixation Fractures, Bone - physiopathology Fractures, Bone - surgery Humans Injuries of the limb. Injuries of the spine Male Medical sciences Middle Aged Prospective Studies Prostheses and Implants Traumas. Diseases due to physical agents Wound Healing |
| title | Multicenter Trial of Collagraft as Bone Graft Substitute |
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