Influence of initial reperfusion pressure after hypothermic cardioplegic ischemia on endothelial modulation of coronary tone in neonatal lambs. Impaired coronary vasodilator response to acetylcholine [published erratum appears in J Thorac Cardiovasc Surg 1991 Oct;102(4):504]

To examine the effect of initial coronary reperfusion pressure on endothelial function, we subjected 16 isolated perfused neonatal lamb hearts to 2 hours of ischemia with potassium cardioplegic solution followed by reperfusion for 1 hour. Before ischemia both acetylcholine, an endothelium-dependent...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 1991-05, Vol.101 (5), p.777-782
Hauptverfasser:	Sawatari, K, Kadoba, K, Bergner, KA, Daitch, JA, Mayer, JE, Jr
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Animals Animals, Newborn Cardioplegic Solutions Coronary Circulation - drug effects Coronary Circulation - physiology Coronary Vessels - drug effects Coronary Vessels - physiology Endothelium - drug effects Endothelium - physiology Hypothermia, Induced In Vitro Techniques Myocardial Reperfusion Nitroglycerin Pressure Sheep Vascular Resistance - drug effects Vascular Resistance - physiology
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