Interleukin 2 induces gamma-interferon production: participation of macrophages and NK-like cells

Interleukin 2 (IL 2) has been shown to be a potent stimulator of natural killer (NK) cells. In the present studies, partially purified mouse and human IL 2 preparations were also found to induce interferon (IFN) from mouse spleen cells. By the criteria of sensitivity to treatment at pH 2 and failure...

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Veröffentlicht in:	The Journal of immunology (1950) 1983-07, Vol.131 (1), p.288-292
Hauptverfasser:	Kawase, I, Brooks, CG, Kuribayashi, K, Olabuenaga, S, Newman, W, Gillis, S, Henney, CS
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Immunity, Cellular Interferon Inducers - pharmacology Interferon-gamma - biosynthesis Interleukin-2 - physiology Killer Cells, Natural - immunology Lymphocyte Cooperation Macrophages - immunology Male Mice Mice, Inbred C57BL Mice, Inbred CBA Mice, Inbred DBA Mice, Nude Spleen - cytology
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