Characterization of the interaction of 5'-p-fluorosulfonylbenzoyl adenosine with the epidermal growth factor receptor/protein kinase in A431 cell membranes

Treatment of membrane vesicles from A431 cells, a human epidermoid carcinoma line, with the affinity label 5'-p-fluorosulfonylbenzoyl [8-14C]adenosine (5'-p-FSO2Bz[14C]Ado) results in an inhibition of the epidermal growth factor (EGF)-stimulable protein kinase and in the modification of pr...

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Veröffentlicht in:	The Journal of biological chemistry 1983-06, Vol.258 (12), p.7824-7827
Hauptverfasser:	Buhrow, S A, Cohen, S, Garbers, D L, Staros, J V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - analogs & derivatives Adenosine - pharmacology Affinity Labels - pharmacology Animals Carcinoma, Squamous Cell Cell Line Cell Membrane - metabolism Epidermal Growth Factor - metabolism ErbB Receptors Molecular Weight Protein Kinases - metabolism Rats Receptors, Cell Surface - isolation & purification Receptors, Cell Surface - metabolism
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