Monoclonal antibodies inhibiting RNA polymerase from Escherichia coli

Monoclonal hybridoma antibodies directed against RNA polymerase from E. coli have been obtained. Only a few have been found to inhibit the enzyme activity. Antibodies produced by two clones, PYN-1 and PYN-2, inhibit RNA polymerase at the stage of RNA chain elongation. the PYN-1 antibodies react with...

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Veröffentlicht in:	FEBS letters 1983-07, Vol.158 (1), p.113-115
Hauptverfasser:	Nikiforov, V.G., Yakubov, L.Z., Bogachova, G.T., Lebedev, A.N., Rokhlin, O.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal DNA-Directed RNA Polymerases - antagonists & inhibitors DNA-Directed RNA Polymerases - immunology Epitopes Escherichia coli Escherichia coli - enzymology Immunoblotting Immunochemistry Monoclonal antibody Radioimmunoassay RNA chain elongation RNA polymerase
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